1. Monash Health
  2. Monash Health research
  3. Books and Book Chapters
Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/26932
Full metadata record
DC FieldValueLanguage
dc.contributor.authorJenkins B.J.en
dc.contributor.authorLundy J.en
dc.contributor.authorSaad M.I.en
dc.date.accessioned2021-05-14T08:59:56Zen
dc.date.available2021-05-14T08:59:56Zen
dc.date.created20210319en
dc.date.issued2021en
dc.identifier.citationMethods in Molecular Biology. 2279 (pp 165-173), 2021. Date of Publication: 2021.en
dc.identifier.issn1064-3745en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/26932en
dc.description.abstractPatient-derived xenografts (PDXs) are created by implanting human tumor tissue or cells into immunodeficent mice, and enable the study of tumor biology, biomarkers and response to therapy in vivo. This chapter describes a method for lung adenocarcinoma (LAC) PDX generation using subcutaneous implantation of tumor tissue and cell suspensions and incorporating the humanization of PDX models by reconstitution with human immune cells.Copyright © 2021, Springer Science+Business Media, LLC, part of Springer Nature.en
dc.languageenen
dc.languageEnglishen
dc.publisherHumana Press Inc.en
dc.relation.ispartofMethods in Molecular Biologyen
dc.titleA Method for the Establishment of Human Lung Adenocarcinoma Patient-Derived Xenografts in Mice.en
dc.typeChapteren
dc.typeChapter-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-0716-1278-1_13en
dc.publisher.placeUnited Statesen
dc.identifier.pubmedid33683693 [http://www.ncbi.nlm.nih.gov/pubmed/?term=33683693]en
dc.identifier.source634494152en
dc.identifier.institution(Lundy, Jenkins, Saad) Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia (Lundy, Jenkins, Saad) Department of Molecular and Translational Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia (Lundy) Department of Surgery, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australiaen
dc.description.addressM.I. Saad, Department of Molecular and Translational Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia. E-mail: Mohamed.saad@hudson.org.auen
dc.description.publicationstatusIn-Processen
dc.rights.statementCopyright 2021 Elsevier B.V., All rights reserved.en
dc.subect.keywordsHumanization Lung adenocarcinoma NOD scid gamma mouse Non-small cell lung cancer Patient-derived xenograften
dc.identifier.authoremailSaad M.I.; Mohamed.saad@hudson.org.auen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeChapter-
item.openairetypeChapter-
item.cerifentitytypePublications-
item.cerifentitytypePublications-
Appears in Collections:Books and Book Chapters
Show simple item record

Page view(s)

136
checked on Nov 24, 2024

Google ScholarTM

Check


Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.