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https://repository.monashhealth.org/monashhealthjspui/handle/1/36950| Title: | Polycystic ovary syndrome and adverse pregnancy outcomes: Current state of knowledge, challenges and potential implications for practice. | Authors: | Moran L.J.;Bahri Khomami M.;Boyle J.A.;Tay C.T.;Vanky E.;Teede H.J. ;Joham A.E. | Institution: | (Bahri Khomami, Boyle, Tay, Teede, Joham, Moran) Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton, VIC, Australia (Boyle) Department of Obstetrics and Gynaecology, Monash Health, Clayton, VIC, Australia (Tay, Teede, Joham, Moran) Department of Endocrinology and Diabetes, Monash Health, Clayton, VIC, Australia (Vanky) Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway (Vanky) Department of Obstetrics and Gynecology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway (Moran) Discipline of Obstetrics and Gynaecology, The Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia | Issue Date: | 7-Jun-2018 | Copyright year: | 2018 | Publisher: | Blackwell Publishing Ltd | Place of publication: | United Kingdom | Publication information: | Clinical Endocrinology. 88 (6) (pp 761-769), 2018. Date of Publication: June 2018. | Journal: | Clinical Endocrinology | Abstract: | Although there is a growing body of literature reporting that pregnancies in women with polycystic ovary syndrome (PCOS) are associated with greater complications than those without PCOS, methodological differences across studies make these results difficult to consolidate. This narrative review outlines potential mechanisms involved in adverse pregnancy outcomes in PCOS and the nature of the complications. It covers limitations of current evidence and future research directions. Future research should include prospective studies with phenotypic stratification of PCOS and matching or consideration of specific PCOS manifestations and risk factors specific to each pregnancy complication. This review also emphasizes the importance of following a healthy lifestyle for women with PCOS and of individualized care according to overall risk factors for pregnancy complications.Copyright © 2018 John Wiley & Sons Ltd | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/cen.13579 | ORCID: | Bahri Khomami, Mahnaz; ORCID: http://orcid.org/0000-0002-5955-1283 Teede, Helena J.; ORCID: http://orcid.org/0000-0001-7609-577X Moran, Lisa J.; ORCID: http://orcid.org/0000-0001-5772-6484 | Link to associated publication: | Click here for full text options | PubMed URL: | 29460303 [http://www.ncbi.nlm.nih.gov/pubmed/?term=29460303] | ISSN: | 0300-0664 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/36950 | Type: | Review | Subjects: | review follitropin inositol luteinizing hormone metformin sex hormone binding globulin personalized medicine *adverse outcome body mass family planning female female infertility gestational weight gain healthy lifestyle human hyperandrogenism inflammation labor complication lifestyle multiple pregnancy obesity *ovary polycystic disease *pregnancy complication *pregnancy outcome prenatal care priority journal *ovary polycystic disease personalized medicine *pregnancy complication *pregnancy outcome prenatal care priority journal Review female female infertility body mass *adverse outcome family planning gestational weight gain healthy lifestyle human hyperandrogenism inflammation labor complication lifestyle multiple pregnancy obesity |
Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
| Appears in Collections: | Articles |
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