Please use this identifier to cite or link to this item:
https://repository.monashhealth.org/monashhealthjspui/handle/1/38189
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Steinfort D.P. | en |
dc.contributor.author | Vazirani J. | en |
dc.contributor.author | Moraes J. | en |
dc.contributor.author | Barnett S. | en |
dc.contributor.author | Johnson D.F. | en |
dc.contributor.author | Knight S. | en |
dc.contributor.author | Miller A. | en |
dc.contributor.author | Wright G. | en |
dc.contributor.author | Alam N.Z. | en |
dc.contributor.author | Conron M. | en |
dc.contributor.author | Irving L.B. | en |
dc.contributor.author | Antippa P. | en |
dc.date.accessioned | 2021-05-14T13:00:58Z | en |
dc.date.available | 2021-05-14T13:00:58Z | en |
dc.date.copyright | 2018 | en |
dc.date.created | 20200929 | en |
dc.date.issued | 2020-09-29 | en |
dc.identifier.citation | ANZ journal of surgery. 88 (12) (pp 1322-1327), 2018. Date of Publication: 01 Dec 2018. | en |
dc.identifier.issn | 1445-2197 (electronic) | en |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/38189 | en |
dc.description.abstract | BACKGROUND: The treatment of choice for early stage non-small cell lung cancer (NSCLC) is surgical resection. Little is known about the short- and long-term outcomes among very elderly patients. We sought to determine predictors of short- and long-term survival among octogenarians undergoing curative-intent resection for NSCLC in Victoria, Australia. METHOD(S): We retrospectively reviewed data from all patients aged >=80 years who underwent curative-intent resection for NSCLC over 12years (January 2005-December 2016) across five tertiary centres. We examined effect of age, stage of disease, extent of surgery and lung function on short- and long-term survival. RESULT(S): Two hundred patients aged >=80 years underwent curative-intent resections. Mortality at 30 and 120days was 2.9% and 5.9%, respectively. Increased early mortality was observed among those >=83years, at 30days (6.8% versus 0.8%, P = 0.044) and 120days (12.2% versus 2.3%, P = 0.0096). Early mortality was highest among patients >=83years requiring lobectomy, compared to sub-lobar resection at 120days (17% versus 3.8%, P = 0.019). Long-term survival was predicted by age and stage of disease. Among patients with Stage I disease aged <83years, lobectomy was associated with superior 5-year survival, compared to sub-lobar resection (83% versus 61%, P = 0.02). CONCLUSION(S): In carefully selected elderly patients undergoing curative-intent resection of early stage NSCLC, both short- and long-term outcomes appear consistent with younger historical cohorts. Early mortality was associated with lobectomy in those with advanced age. Older patients undergoing lobectomy appeared to be at highest risk for early mortality, while younger patients with Stage I disease undergoing at least lobectomy appear to have the best long-term survival.Copyright © 2018 Royal Australasian College of Surgeons. | en |
dc.language | en | en |
dc.language | English | en |
dc.publisher | NLM (Medline) | en |
dc.relation.ispartof | ANZ Journal of Surgery | - |
dc.subject.mesh | lung tumor | - |
dc.subject.mesh | lung tumor [Surgery] | - |
dc.subject.mesh | cancer staging | - |
dc.subject.mesh | epidemiology | - |
dc.subject.mesh | lung resection | - |
dc.subject.mesh | non small cell lung cancer | - |
dc.subject.mesh | non small cell lung cancer [Surgery] | - |
dc.subject.mesh | procedures | - |
dc.subject.mesh | time factor | - |
dc.subject.mesh | very elderly | - |
dc.subject.mesh | Victoria | - |
dc.title | Outcomes following resection of non-small cell lung cancer in octogenarians. | en |
dc.type | Article | en |
dc.identifier.affiliation | Respiratory and Sleep Medicine | en |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/ans.14861 | - |
dc.publisher.place | Australia | en |
dc.identifier.pubmedid | 30277303 [http://www.ncbi.nlm.nih.gov/pubmed/?term=30277303] | en |
dc.identifier.source | 628412797 | en |
dc.identifier.institution | (Vazirani, Moraes, Irving, Steinfort) Department of Respiratory and Sleep Medicine, Royal Melbourne Hospital, Melbourne, VIC, Australia (Barnett, Wright, Antippa) Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia (Barnett, Knight) Department of Thoracic Surgery, Austin Hospital, Melbourne, VIC, Australia (Barnett, Wright, Antippa) Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia (Barnett, Knight, Wright, Alam, Antippa) Department of Surgery, University of Melbourne, Melbourne, VIC, Australia (Johnson) Department of Medicine, Royal Melbourne Hospital, Melbourne, VIC, Australia (Johnson, Irving, Steinfort) Department of Medicine, University of Melbourne, Melbourne, VIC, Australia (Miller) Department of Respiratory and Sleep Medicine, Monash Health, Melbourne, VIC, Australia (Wright, Alam) Department of Cardiothoracic Surgery, St Vincent's Hospital, Melbourne, VIC, Australia (Conron) Department of Respiratory and Sleep Medicine, St Vincent's Hospital, Melbourne, VIC, Australia (Conron, Irving, Steinfort) Department of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia | en |
dc.rights.statement | This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine | en |
dc.subect.keywords | non-small cell lung cancer octogenarian survival | en |
dc.identifier.affiliationext | (Vazirani, Moraes, Irving, Steinfort) Department of Respiratory and Sleep Medicine, Royal Melbourne Hospital, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Barnett, Wright, Antippa) Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Barnett, Knight) Department of Thoracic Surgery, Austin Hospital, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Barnett, Wright, Antippa) Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Barnett, Knight, Wright, Alam, Antippa) Department of Surgery, University of Melbourne, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Johnson) Department of Medicine, Royal Melbourne Hospital, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Johnson, Irving, Steinfort) Department of Medicine, University of Melbourne, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Wright, Alam) Department of Cardiothoracic Surgery, St Vincent's Hospital, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Conron) Department of Respiratory and Sleep Medicine, St Vincent's Hospital, Melbourne, VIC, Australia | - |
dc.identifier.affiliationext | (Conron, Irving, Steinfort) Department of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia | - |
dc.identifier.affiliationmh | (Miller) Department of Respiratory and Sleep Medicine, Monash Health, Melbourne, VIC, Australia | - |
item.fulltext | No Fulltext | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | Articles |
Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.