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https://repository.monashhealth.org/monashhealthjspui/handle/1/51815| Chapter/Book title: | Patient-derived xenograft models for ovarian cancer. | Authors: | Tran T.M.;Ho G.Y. ;Chu S. | Institution: | (Tran, Chu) Hudson Institute of Medical Research, Clayton, VIC, Australia (Tran, Ho) School of Clinical Sciences, Monash University, Clayton, VIC, Australia (Ho) Monash Health, Clayton, VIC, Australia |
Publication year: | 20-May-2024 | Copyright year: | 2024 | Publisher: | Humana Press Inc. | Place of publication: | United States | Publication information: | Methods in Molecular Biology. 2806(pp 187-196), 2024. Date of Publication: 2024. | Book title: | Methods in Molecular Biology | Abstract: | Patient-derived xenograft (PDX) models play a crucial role for in vivo research. They maintain the original molecular characteristics of the human tumor and provide a more accurate tumor microenvironment, which cannot be replicated by in vitro models. This chapter describes four different transplantation methods, namely, intra-bursal, intrarenal capsule, intraperitoneal, and subcutaneous, to develop PDX models for ovarian cancer research.Copyright © The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2024. | DOI: | http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1007/978-1-0716-3858-3_13 | PubMed URL: | 38676803 [https://www.ncbi.nlm.nih.gov/pubmed/?term=38676803] | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/51815 | Type: | Chapter | Subjects: | cancer research cancer transplantation granulosa cell tumor orthotopic transplantation ovary cancer tumor biopsy |
| Appears in Collections: | Books and Book Chapters |
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