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DC Field | Value | Language |
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dc.contributor.author | Wood C. | en |
dc.contributor.author | Tiglias J. | en |
dc.contributor.author | Wilton L. | en |
dc.contributor.author | Trounson A. | en |
dc.contributor.author | Barnes F.L. | en |
dc.contributor.author | Kausche A. | en |
dc.date.accessioned | 2021-05-14T09:00:12Z | en |
dc.date.available | 2021-05-14T09:00:12Z | en |
dc.date.copyright | 1996 | en |
dc.date.created | 19960607 | en |
dc.date.issued | 2012-10-22 | en |
dc.identifier.citation | Fertility and Sterility. 65 (6) (pp 1151-1156), 1996. Date of Publication: 1996. | en |
dc.identifier.issn | 0015-0282 | en |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/26944 | en |
dc.description.abstract | Objective: To determine the factors that influence the number and quality of embryos produced from primary oocytes collected from untreated regularly ovulating and irregular or anovulatory polycystic women. Design(s): A direct comparison between two patient groups whose oocytes were matured in vitro and a comparison of the embryo development of in vitro-matured oocytes from untreated patients with in vivo-matured oocytes of superovulated IVF-ET patients obtained during the same period. Setting(s): The Monash IVF Clinic, involving patients who expressed the desire to avoid superovulation with fertility drugs. Main Outcome Measure(s): The completion of nuclear maturation of oocytes after 36 or 48 hours culture, fertilization in vitro, and embryo development ratio. Result(s): Oocytes from regular cycling patients matured and fertilized at significantly higher rates than irregular cycling and anovulatory women and their embryos had significantly higher mean embryo development ratio. The mean embryo development ratio of embryos of regular cycling patients was similar to superovulated IVF patients but irregular cycling and anovulatory patients had a significantly lower embryo development ratio. Culture of oocytes for 48 hours increased maturation of oocytes from 57% to 82% but did not affect fertilization or cleavage rates. Embryo development was not affected significantly by the grade of follicular cell cover of oocytes. Conclusion(s): The developmental capability of primary oocytes is higher in regular cycling women than in irregular cycling and anovulatory women with polycystic ovary disease. | en |
dc.language | en | en |
dc.language | English | en |
dc.publisher | Elsevier Inc. | en |
dc.publisher | Elsevier Inc. (360 Park Avenue South, New York NY 10010, United States) | en |
dc.relation.ispartof | Fertility and Sterility | en |
dc.title | Production of embryos from in vitro-matured primary human oocytes. | en |
dc.type | Article | en |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1016/s0015-0282%2816%2958330-7 | en |
dc.publisher.place | United States | en |
dc.identifier.pubmedid | 8641489 [http://www.ncbi.nlm.nih.gov/pubmed/?term=8641489] | en |
dc.identifier.source | 26158631 | en |
dc.identifier.institution | (Barnes, Kausche, Tiglias, Wood, Wilton, Trounson) Inst. of Reproduction/Development, Monash Medical Centre, 246 Clayton Road, Clayton, Vic. 3168, Australia | en |
dc.description.address | A. Trounson, Inst. of Reproduction/Development, Monash Medical Centre, 246 Clayton Road, Clayton, Vic. 3168, Australia | en |
dc.description.publicationstatus | Embase | en |
dc.rights.statement | Copyright 2021 Elsevier B.V., All rights reserved. | en |
dc.rights.statement | Copyright 2012 Elsevier B.V., All rights reserved. | en |
dc.subect.keywords | embryo development immature oocyte collection in vitro maturation IVF Primary oocytes | en |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | Article | - |
Appears in Collections: | Articles |
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