1. Monash Health
  2. Monash Health research
  3. Articles
Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/27288
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHodgson S.en
dc.contributor.authorDe Vivo I.en
dc.contributor.authorDennis J.en
dc.contributor.authorDork T.en
dc.contributor.authorDowdy S.C.en
dc.contributor.authorDunning A.M.en
dc.contributor.authorDurst M.en
dc.contributor.authorEaston D.F.en
dc.contributor.authorEkici A.B.en
dc.contributor.authorFasching P.A.en
dc.contributor.authorFridley B.L.en
dc.contributor.authorFriedenreich C.M.en
dc.contributor.authorGarcia-Closas M.en
dc.contributor.authorGaudet M.M.en
dc.contributor.authorGiles G.G.en
dc.contributor.authorGoode E.L.en
dc.contributor.authorGorman M.en
dc.contributor.authorHaiman C.A.en
dc.contributor.authorHall P.en
dc.contributor.authorHankinson S.E.en
dc.contributor.authorHein A.en
dc.contributor.authorHillemanns P.en
dc.contributor.authorHoivik E.A.en
dc.contributor.authorHolliday E.G.en
dc.contributor.authorHunter D.J.en
dc.contributor.authorKraft P.en
dc.contributor.authorKrakstad C.en
dc.contributor.authorLambrechts D.en
dc.contributor.authorLe Marchand L.en
dc.contributor.authorLiang X.en
dc.contributor.authorLindblom A.en
dc.contributor.authorLissowska J.en
dc.contributor.authorLong J.en
dc.contributor.authorLu L.en
dc.contributor.authorMagliocco A.M.en
dc.contributor.authorMartin L.en
dc.contributor.authorMcEvoy M.en
dc.contributor.authorMilne R.L.en
dc.contributor.authorMints M.en
dc.contributor.authorNassir R.en
dc.contributor.authorOtton G.en
dc.contributor.authorPalles C.en
dc.contributor.authorPooler L.en
dc.contributor.authorProietto T.en
dc.contributor.authorRebbeck T.R.en
dc.contributor.authorRenner S.P.en
dc.contributor.authorRisch H.A.en
dc.contributor.authorRubner M.en
dc.contributor.authorRunnebaum I.en
dc.contributor.authorSacerdote C.en
dc.contributor.authorSarto G.E.en
dc.contributor.authorSchumacher F.en
dc.contributor.authorScott R.J.en
dc.contributor.authorSetiawan V.W.en
dc.contributor.authorShah M.en
dc.contributor.authorSheng X.en
dc.contributor.authorShu X.-O.en
dc.contributor.authorSouthey M.C.en
dc.contributor.authorTham E.en
dc.contributor.authorTomlinson I.en
dc.contributor.authorTrovik J.en
dc.contributor.authorTurman C.en
dc.contributor.authorTyrer J.P.en
dc.contributor.authorVan Den Berg D.en
dc.contributor.authorWang Z.en
dc.contributor.authorWentzensen N.en
dc.contributor.authorXia L.en
dc.contributor.authorXiang Y.-B.en
dc.contributor.authorYang H.P.en
dc.contributor.authorYu H.en
dc.contributor.authorZheng W.en
dc.contributor.authorWebb P.M.en
dc.contributor.authorThompson D.J.en
dc.contributor.authorSpurdle A.B.en
dc.contributor.authorGlubb D.M.en
dc.contributor.authorO'Mara T.A.en
dc.contributor.authorChen C.en
dc.contributor.authorJones A.en
dc.contributor.authorKho P.-F.en
dc.contributor.authorAmant F.en
dc.contributor.authorAnnibali D.en
dc.contributor.authorAshton K.en
dc.contributor.authorAttia J.en
dc.contributor.authorAuer P.L.en
dc.contributor.authorBeckmann M.W.en
dc.contributor.authorBlack A.en
dc.contributor.authorBrinton L.en
dc.contributor.authorBuchanan D.D.en
dc.contributor.authorChanock S.J.en
dc.contributor.authorChen M.M.en
dc.contributor.authorCheng T.H.T.en
dc.contributor.authorCook L.S.en
dc.contributor.authorCrous-Bous M.en
dc.contributor.authorCzene K.en
dc.date.accessioned2021-05-14T09:08:48Zen
dc.date.available2021-05-14T09:08:48Zen
dc.date.copyright2021en
dc.date.created20210217en
dc.date.issued2021-02-17en
dc.identifier.citationInternational Journal of Cancer. 148 (2) (pp 307-319), 2021. Date of Publication: 15 Jan 2021.en
dc.identifier.issn0020-7136en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/27288en
dc.description.abstractBlood lipids have been associated with the development of a range of cancers, including breast, lung and colorectal cancer. For endometrial cancer, observational studies have reported inconsistent associations between blood lipids and cancer risk. To reduce biases from unmeasured confounding, we performed a bidirectional, two-sample Mendelian randomization analysis to investigate the relationship between levels of three blood lipids (low-density lipoprotein [LDL] and high-density lipoprotein [HDL] cholesterol, and triglycerides) and endometrial cancer risk. Genetic variants associated with each of these blood lipid levels (P < 5 x 10-8) were identified as instrumental variables, and assessed using genome-wide association study data from the Endometrial Cancer Association Consortium (12 906 cases and 108 979 controls) and the Global Lipids Genetic Consortium (n = 188 578). Mendelian randomization analyses found genetically raised LDL cholesterol levels to be associated with lower risks of endometrial cancer of all histologies combined, and of endometrioid and non-endometrioid subtypes. Conversely, higher genetically predicted HDL cholesterol levels were associated with increased risk of non-endometrioid endometrial cancer. After accounting for the potential confounding role of obesity (as measured by genetic variants associated with body mass index), the association between genetically predicted increased LDL cholesterol levels and lower endometrial cancer risk remained significant, especially for non-endometrioid endometrial cancer. There was no evidence to support a role for triglycerides in endometrial cancer development. Our study supports a role for LDL and HDL cholesterol in the development of non-endometrioid endometrial cancer. Further studies are required to understand the mechanisms underlying these findings.Copyright © 2020 Union for International Cancer Controlen
dc.languageEnglishen
dc.languageenen
dc.publisherWiley-Liss Inc.en
dc.relation.ispartofInternational Journal of Canceren
dc.subjecthistopathologyen
dc.subjecthigh density lipoprotein cholesterol levelen
dc.subjectarticleen
dc.subjectbody massen
dc.subjectgenetic variationen
dc.subjecttriacylglycerol/ec [Endogenous Compound]en
dc.subjectlow density lipoprotein cholesterol/ec [Endogenous Compound]en
dc.subjecthigh density lipoprotein cholesterol/ec [Endogenous Compound]en
dc.subject*cholesterolen
dc.subjecttriacylglycerol blood levelen
dc.subjectsingle nucleotide polymorphismen
dc.subjectpriority journalen
dc.subjectpredictionen
dc.subject*Mendelian randomization analysisen
dc.subjectmajor clinical studyen
dc.subjectlow density lipoprotein cholesterol levelen
dc.subjecthumanen
dc.subjectgenome-wide association studyen
dc.subjectcancer classificationen
dc.subject*cancer risken
dc.subjectcontrolled studyen
dc.subjectdisease associationen
dc.subjectdisease risk assessmenten
dc.subject*endometrium cancer/et [Etiology]en
dc.subjectfemaleen
dc.subjectgene identificationen
dc.titleMendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer.en
dc.typeArticleen
dc.identifier.doihttp://monash.idm.oclc.org/login?url=-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1002/ijc.33206en
dc.publisher.placeUnited Statesen
dc.identifier.pubmedid32851660 [http://www.ncbi.nlm.nih.gov/pubmed/?term=32851660]en
dc.identifier.source2005790081en
dc.identifier.institution(Kho, Spurdle, Glubb, O'Mara) Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia (Kho) School of Biomedical Science, Queensland University of Technology, Brisbane, QLD, Australia (Amant, Annibali) Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium (Ashton, Attia, Holliday, Scott) Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia (Ashton) Centre for Information Based Medicine, University of Newcastle, Callaghan, NSW, Australia (Ashton, Scott) Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia (Attia, Holliday, McEvoy) Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia (Auer) Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, United States (Auer) Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, United States (Beckmann, Fasching, Hein) Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany (Black, Brinton, Wang, Wentzensen, Yang) Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States (Buchanan, Southey) Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia (Buchanan, Giles, Milne) Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia (Buchanan) Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, VIC, Australia (Buchanan) University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, VIC, Australia (Chanock, Garcia-Closas) Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States (Chen) Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, United States (Chen, Crous-Bous, De Vivo, Hunter, Kraft, Turman) Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States (Cheng, Gorman, Jones, Palles, Tomlinson) Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom (Cook) University of New Mexico Health Sciences Center, Albuquerque, NM, United States (Cook, Friedenreich) Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, AB, Canada (Crous-Bous, De Vivo, Hankinson) Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States (Czene, Hall) Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dennis, Easton, Thompson) Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom (Dork, Hillemanns) Gynaecology Research Unit, Hannover Medical School, Hannover, Germany (Dowdy) Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, MN, United States (Dunning, Easton, Shah, Tyrer) Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom (Durst, Runnebaum) Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany (Ekici) Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany (Fasching) David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, United States (Fridley) Department of Biostatistics, Kansas University Medical Center, Kansas City, KS, United States (Gaudet) Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, United States (Giles, Milne, Southey) Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia (Giles, Milne, Southey) Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia (Goode) Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, United States (Haiman, Pooler, Setiawan, Sheng, Van Den Berg, Xia) Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States (Hall) Department of Oncology, Sodersjukhuset, Stockholm, Sweden (Hankinson) Department of Biostatistics & Epidemiology, University of Massachusetts, Amherst, Amherst, MA, United States (Hodgson) Department of Clinical Genetics, St George's, University of London, London, United Kingdom (Hoivik, Krakstad, Trovik) Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway (Hoivik, Krakstad, Trovik) Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway (Hunter, Kraft) Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States (Hunter) Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom (Lambrechts) VIB Center for Cancer Biology, Leuven, Belgium (Lambrechts) Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium (Le Marchand, Yu) Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, United States (Liang) Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, United States (Lindblom, Tham) Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden (Lindblom) Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden (Lissowska) Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Cancer Center, Oncology Institute, Warsaw, Poland (Long, Shu, Zheng) Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States (Lu, Risch) Chronic Disease Epidemiology, Yale School of Medicine, New Haven, CT, United States (Magliocco) Department of Anatomic Pathology, Moffitt Cancer Center & Research Institute, Tampa, FL, United States (Martin, Tomlinson) Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom (Mints) Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden (Nassir) Department of Biochemistry and Molecular Medicine, University of California Davis, Davis, CA, United States (Otton, Proietto) School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia (Rebbeck) Harvard T.H. Chan School of Public Health, Boston, MA, United States (Rebbeck) Dana-Farber Cancer Institute, Boston, MA, United States (Renner, Rubner) Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany (Sacerdote) Center for Cancer Prevention (CPO-Peimonte), Turin, Italy (Sacerdote) Human Genetics Foundation (HuGeF), Turin, Italy (Sarto) Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States (Schumacher) Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States (Scott) Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, NSW, Australia (Tham) Clinical Genetics, Karolinska Institutet, Stockholm, Sweden (Xiang) State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China (Webb) Population Health Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australiaen
dc.description.addressT.A. O'Mara, Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia. E-mail: tracy.omara@qimrberghofer.edu.auen
dc.subject.keywordsingle nucleotide polymorphismen
dc.subject.keywordhumanen
dc.subject.keywordlow density lipoprotein cholesterol levelen
dc.subject.keywordmajor clinical studyen
dc.subject.keyword*Mendelian randomization analysisen
dc.subject.keywordpredictionen
dc.subject.keywordpriority journalen
dc.subject.keywordtriacylglycerol blood levelen
dc.subject.keywordArticleen
dc.subject.keywordbody massen
dc.subject.keywordcancer classificationen
dc.subject.keyword*cancer risken
dc.subject.keywordcontrolled studyen
dc.subject.keyworddisease associationen
dc.subject.keyworddisease risk assessmenten
dc.subject.keyword*endometrium cancer / *etiologyen
dc.subject.keywordfemaleen
dc.subject.keywordgene identificationen
dc.subject.keywordgenetic variationen
dc.subject.keywordgenome-wide association studyen
dc.subject.keywordhigh density lipoprotein cholesterol levelen
dc.subject.keywordhistopathologyen
dc.relation.libraryurlLibKey Linken
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2021 Elsevier B.V., All rights reserved.en
dc.subect.keywordsendometrial cancer risk HDL cholesterol LDL cholesterol Mendelian randomization triglyceridesen
dc.identifier.authoremailO'Mara T.A.; tracy.omara@qimrberghofer.edu.auen
dc.description.grantOrganization: (BCRF) *Breast Cancer Research Foundation* Organization No: 100001006 Country: United States Organization: (MFMER) *Mayo Foundation for Medical Education and Research* Organization No: 100007048 Country: United States Organization: (NCS) *Kreftforeningen* Organization No: 100008730 Country: Norway Organization: (NHLBI) *National Heart, Lung, and Blood Institute* Organization No: 100000050 Country: United States Organization: (OCRF) *Ovarian Cancer Research Fund* Organization No: 100001282 Country: United States Organization: (SGK) *Susan G. Komen* Organization No: 100009634 Country: United States Organization: *Fred Hutchinson Cancer Research Center* Organization No: 100005895 Country: United States Organization: *Haukeland Universitetssjukehus* Organization No: 501100010586 Country: Norway No: C12292/A11174 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C1281/A12014 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C1287/A10118 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C1287/A10710 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C490/A10124 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C5047/A10692 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C5047/A15007 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C5047/A8384 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: C8197/A16565 Organization: (CRUK) *Cancer Research UK* Organization No: 501100000289 Country: United Kingdom No: CA1X01HG007491-01 Organization: (NIH) *National Institutes of Health* Organization No: 100000002 Country: United States No: G0000934 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia No: HHSN268201100001C Organization: (HHS;USDHHS;DHHS) *U.S. Department of Health and Human Services* Organization No: 100000016 Country: United States No: HHSN268201100002C Organization: (HHS;USDHHS;DHHS) *U.S. Department of Health and Human Services* Organization No: 100000016 Country: United States No: HHSN268201100003C Organization: (HHS;USDHHS;DHHS) *U.S. Department of Health and Human Services* Organization No: 100000016 Country: United States No: HHSN268201100004C Organization: (HHS;USDHHS;DHHS) *U.S. Department of Health and Human Services* Organization No: 100000016 Country: United States No: HHSN268201100046C Organization: (HHS;USDHHS;DHHS) *U.S. Department of Health and Human Services* Organization No: 100000016 Country: United States No: HHSN271201100004C Organization: (HHS;USDHHS;DHHS) *U.S. Department of Health and Human Services* Organization No: 100000016 Country: United States No: ID#1031333 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia No: ID#1109286 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia No: ID#339435 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia No: ID#403031 Organization: *Cancer Council Tasmania* Organization No: 501100001169 Country: Australia No: ID#457636 Organization: *Cancer Council Tasmania* Organization No: 501100001169 Country: Australia No: ID#552402 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia No: MOP-86727 Organization: (CIHR;IRSC) *Canadian Institutes of Health Research* Organization No: 501100000024 Country: Canada No: R01-CA058598 Organization: (NIH) *National Institutes of Health* Organization No: 100000002 Country: United States No: R01-CA149429 Organization: (NIH) *National Institutes of Health* Organization No: 100000002 Country: United States No: U19 CA148065-01 Organization: (NCI) *National Cancer Institute* Organization No: 100000054 Country: United States No: U19-CA148112 Organization: (NIH) *National Institutes of Health* Organization No: 100000002 Country: United States No: W81XWH-10-1-0341 Organization: *Department of Defence, Australian Government* Organization No: 501100001029 Country: Australiaen
dc.identifier.affiliationext(Kho, Spurdle, Glubb, O'Mara) Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia-
dc.identifier.affiliationext(Kho) School of Biomedical Science, Queensland University of Technology, Brisbane, QLD, Australia-
dc.identifier.affiliationext(Amant, Annibali) Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospitals KU Leuven, University of Leuven, Leuven, Belgium-
dc.identifier.affiliationext(Ashton, Attia, Holliday, Scott) Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia-
dc.identifier.affiliationext(Ashton) Centre for Information Based Medicine, University of Newcastle, Callaghan, NSW, Australia-
dc.identifier.affiliationext(Ashton, Scott) Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia-
dc.identifier.affiliationext(Attia, Holliday, McEvoy) Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia-
dc.identifier.affiliationext(Auer) Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, United States-
dc.identifier.affiliationext(Auer) Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, United States-
dc.identifier.affiliationext(Beckmann, Fasching, Hein) Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany-
dc.identifier.affiliationext(Black, Brinton, Wang, Wentzensen, Yang) Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States-
dc.identifier.affiliationext(Buchanan, Southey) Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia-
dc.identifier.affiliationext(Buchanan, Giles, Milne) Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia-
dc.identifier.affiliationext(Buchanan) Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, Parkville, VIC, Australia-
dc.identifier.affiliationext(Buchanan) University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, VIC, Australia-
dc.identifier.affiliationext(Chanock, Garcia-Closas) Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States-
dc.identifier.affiliationext(Chen) Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, United States-
dc.identifier.affiliationext(Chen, Crous-Bous, De Vivo, Hunter, Kraft, Turman) Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States-
dc.identifier.affiliationext(Cheng, Gorman, Jones, Palles, Tomlinson) Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom-
dc.identifier.affiliationext(Cook) University of New Mexico Health Sciences Center, Albuquerque, NM, United States-
dc.identifier.affiliationext(Cook, Friedenreich) Department of Cancer Epidemiology and Prevention Research, Alberta Health Services, Calgary, AB, Canada-
dc.identifier.affiliationext(Crous-Bous, De Vivo, Hankinson) Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States-
dc.identifier.affiliationext(Czene, Hall) Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden-
dc.identifier.affiliationext(Dennis, Easton, Thompson) Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom-
dc.identifier.affiliationext(Dork, Hillemanns) Gynaecology Research Unit, Hannover Medical School, Hannover, Germany-
dc.identifier.affiliationext(Dowdy) Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, MN, United States-
dc.identifier.affiliationext(Dunning, Easton, Shah, Tyrer) Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom-
dc.identifier.affiliationext(Durst, Runnebaum) Department of Gynaecology, Jena University Hospital - Friedrich Schiller University, Jena, Germany-
dc.identifier.affiliationext(Ekici) Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany-
dc.identifier.affiliationext(Fasching) David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, United States-
dc.identifier.affiliationext(Fridley) Department of Biostatistics, Kansas University Medical Center, Kansas City, KS, United States-
dc.identifier.affiliationext(Gaudet) Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, United States-
dc.identifier.affiliationext(Giles, Milne, Southey) Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia-
dc.identifier.affiliationext(Goode) Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, United States-
dc.identifier.affiliationext(Haiman, Pooler, Setiawan, Sheng, Van Den Berg, Xia) Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States-
dc.identifier.affiliationext(Hall) Department of Oncology, Sodersjukhuset, Stockholm, Sweden-
dc.identifier.affiliationext(Hankinson) Department of Biostatistics & Epidemiology, University of Massachusetts, Amherst, Amherst, MA, United States-
dc.identifier.affiliationext(Hodgson) Department of Clinical Genetics, St George's, University of London, London, United Kingdom-
dc.identifier.affiliationext(Hoivik, Krakstad, Trovik) Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway-
dc.identifier.affiliationext(Hoivik, Krakstad, Trovik) Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway-
dc.identifier.affiliationext(Hunter, Kraft) Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, United States-
dc.identifier.affiliationext(Hunter) Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom-
dc.identifier.affiliationext(Lambrechts) VIB Center for Cancer Biology, Leuven, Belgium-
dc.identifier.affiliationext(Lambrechts) Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium-
dc.identifier.affiliationext(Le Marchand, Yu) Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, United States-
dc.identifier.affiliationext(Liang) Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, United States-
dc.identifier.affiliationext(Lindblom, Tham) Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden-
dc.identifier.affiliationext(Lindblom) Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden-
dc.identifier.affiliationext(Lissowska) Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Cancer Center, Oncology Institute, Warsaw, Poland-
dc.identifier.affiliationext(Long, Shu, Zheng) Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States-
dc.identifier.affiliationext(Lu, Risch) Chronic Disease Epidemiology, Yale School of Medicine, New Haven, CT, United States-
dc.identifier.affiliationext(Magliocco) Department of Anatomic Pathology, Moffitt Cancer Center & Research Institute, Tampa, FL, United States-
dc.identifier.affiliationext(Martin, Tomlinson) Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom-
dc.identifier.affiliationext(Mints) Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden-
dc.identifier.affiliationext(Nassir) Department of Biochemistry and Molecular Medicine, University of California Davis, Davis, CA, United States-
dc.identifier.affiliationext(Otton, Proietto) School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia-
dc.identifier.affiliationext(Rebbeck) Harvard T.H. Chan School of Public Health, Boston, MA, United States-
dc.identifier.affiliationext(Rebbeck) Dana-Farber Cancer Institute, Boston, MA, United States-
dc.identifier.affiliationext(Renner, Rubner) Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany-
dc.identifier.affiliationext(Sacerdote) Center for Cancer Prevention (CPO-Peimonte), Turin, Italy-
dc.identifier.affiliationext(Sacerdote) Human Genetics Foundation (HuGeF), Turin, Italy-
dc.identifier.affiliationext(Sarto) Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States-
dc.identifier.affiliationext(Schumacher) Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States-
dc.identifier.affiliationext(Scott) Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, NSW, Australia-
dc.identifier.affiliationext(Tham) Clinical Genetics, Karolinska Institutet, Stockholm, Sweden-
dc.identifier.affiliationext(Xiang) State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China-
dc.identifier.affiliationext(Webb) Population Health Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia-
dc.identifier.affiliationmh(Giles, Milne, Southey) Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeArticle-
crisitem.author.deptOphthalmology-
crisitem.author.deptEndocrinology-
Appears in Collections:Articles
Show simple item record

Page view(s)

70
checked on Jul 8, 2024

Google ScholarTM

Check


Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.