Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/27668
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dc.contributor.authorMehta V.en
dc.contributor.authorJaremko J.L.en
dc.contributor.authorJans L.en
dc.contributor.authorBhargava R.en
dc.contributor.authorColeman L.T.en
dc.contributor.authorDitchfield M.R.en
dc.contributor.authorAu Yong K.J.en
dc.date.accessioned2021-05-14T09:19:02Zen
dc.date.available2021-05-14T09:19:02Zen
dc.date.copyright2013en
dc.date.created20130607en
dc.date.issued2013-06-07en
dc.identifier.citationPediatric Radiology. 43 (3) (pp 347-354), 2013. Date of Publication: March 2013.en
dc.identifier.issn0301-0449en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/27668en
dc.description.abstractBackground: Supratentorial atypical teratoid rhabdoid tumor (ATRT) in many cases has a distinctive appearance on post-gadolinium MRI. Objective(s): We sought to determine whether this is a unique appearance allowing ATRT to be distinguished accurately from other types of pediatric supratentorial tumors. Material(s) and Method(s): Retrospective review of all available preoperative MRI of pediatric supratentorial tumors at two tertiary children's hospitals, and systematic literature review of case series and reports describing the MRI imaging appearances of supratentorial ATRT. Result(s): We had 61 supratentorial tumors, including 32 gliomas, 6 ATRT, 8 ependymomas, 6 gangliogliomas, 2 pilomyxoid astrocytomas, 3 primitive neuro-ectodermal tumors, 2 choroid plexus papillomas, and 2 meningiomas. ATRT presented in significantly younger patients than astrocytomas (mean age 2.6 years vs. 9.9 years, P < 0.05). The visual pattern of a thick, wavy (irregular) heterogeneously enhancing wall around a cystic center was seen in 5/6 (83%) ATRTs and only 3/55 (5.4%) other tumors (P < 0.0001), for specificity of 95%, sensitivity of 83%, positive predictive value of 63% and a negative predictive value of 95%. Conclusion(s): A supratentorial tumor with a thick, wavy (irregular) heterogeneously enhancing wall surrounding a central cystic region is suggestive of ATRT in the appropriate clinical setting, especially in a child of preschool age. © 2012 Springer-Verlag Berlin Heidelberg.en
dc.languageEnglishen
dc.languageenen
dc.publisherSpringer Verlag (Tiergartenstrasse 17, Heidelberg D-69121, Germany)en
dc.titleHow specific is the MRI appearance of supratentorial atypical teratoid rhabdoid tumors?.en
dc.typeArticleen
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1007/s00247-012-2530-zen
dc.publisher.placeGermanyen
dc.identifier.pubmedid23143401 [http://www.ncbi.nlm.nih.gov/pubmed/?term=23143401]en
dc.identifier.source52298258en
dc.identifier.institution(Au Yong, Jaremko, Bhargava) Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, 8440-112 Street, Edmonton, NW T6G 2B7, Canada (Jans) Department of Radiology and Medical Imaging, Ghent University Hospital, Gent, Belgium (Coleman) Department of Radiology and Pediatrics, University of Melbourne, Murdoch Children's Research Institute, Melbourne, Australia (Coleman) Medical Imaging, Royal Children's Hospital, Parkville, Australia (Mehta) Department of Neurosurgery, University of Alberta Hospital, Edmonton, Canada (Ditchfield) Diagnostic Imaging, Monash Children's and Monash University, Monash Medical Centre, Clayton, Australiaen
dc.description.addressK.J. Au Yong, Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, 8440-112 Street, Edmonton, NW T6G 2B7, Canada. E-mail: kong.auyong@gmail.comen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2013 Elsevier B.V., All rights reserved.en
dc.subect.keywordsAtypical teratoid rhabdoid tumor Brain tumor MRI Supratentorial tumoren
dc.identifier.authoremailAu Yong K.J.; kong.auyong@gmail.comen
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeArticle-
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