Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/27840
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dc.contributor.authorCooper B.en
dc.contributor.authorBranley P.en
dc.contributor.authorCollins J.en
dc.contributor.authorCraig J.en
dc.contributor.authorPilmore A.en
dc.contributor.authorKesselhut J.en
dc.contributor.authorHarris D.en
dc.contributor.authorWong M.G.en
dc.contributor.authorJohnson D.W.en
dc.contributor.authorPollock C.en
dc.date.accessioned2021-05-14T09:22:32Zen
dc.date.available2021-05-14T09:22:32Zen
dc.date.copyright2013en
dc.date.created20140309en
dc.date.issued2014-03-12en
dc.identifier.citationNephrology. Conference: 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology. Brisbane, QLD Australia. Conference Publication: (var.pagings). 18 (SUPPL. 1) (pp 17), 2013. Date of Publication: September 2013.en
dc.identifier.issn1320-5358en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/27840en
dc.description.abstractBackground and Aims: The Initiating Dialysis Early and Late (IDEAL) study demonstrated that planned early or late initiation of dialysis, based on the Cockcroft and Gault (CG) estimation of glomerular filtration rate (eGFR), was associated with identical clinical outcomes. This study was a pre-specified analysis examining the association of all-cause mortality with eGFR, measured by the CG,Modification of Diet in Renal Disease (MDRD) or the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) formulae at the time of commencement of dialysis. Method(s): IDEAL trial participants were allocated into tertiles according to the CG, MDRD and CKD-EPI formulae at dialysis commencement. The patient survival was assessed using the Kaplan-Meier method. Result(s): There was no difference in survival among patients when stratified into tertiles of GFR according to the CG formula. However, there was a significant survival benefit in the tertile of patients starting dialysis with the lowest eGFR when the MDRD or CKD-EPI was applied (p < 0.01), independent of correction for body surface area. An increased hazard ratio for death was observed in older females and patients with diabetes and cardiovascular disease independent of the formula used. Conclusion(s): Discrepancies exist in the relationship between eGFR at dialysis commencement and mortality in patients with stage 5 CKD depending on the formula used. Patients commencing dialysis with a higher eGFR were more likely to be older, Caucasian and have a history of ischemic heart disease, suggesting that observational studies demonstrating a survival benefit in patients who start dialysis 'late' is due to reduced comorbidity.en
dc.languageEnglishen
dc.languageenen
dc.publisherBlackwell Publishingen
dc.titleThe association between glomerular filtration rate estimated by multiple methods at dialysis commencement and patient survival in the ideal trial.en
dc.typeConference Abstracten
dc.type.studyortrialObservational study (cohort, case-control, cross sectional or survey)-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/nep.12121en
local.date.conferencestart2013-09-09en
dc.identifier.source71356992en
dc.identifier.institution(Wong, Pollock, Cooper, Kesselhut) Department of Renal Medicine, Royal North Shore Hospital, Sydney Medical School, Australia (Branley) Monash Medical Centre and Eastern Health Renal Units, Australia (Collins) Department of Medicine, University of Auckland, Auckland City Hospital, New Zealand (Craig) Department of Nephrology, Children's Hospital at Westmead, Sydney School of Public Health, Australia (Pilmore) School of Health and Social Development, Deakin University, Australia (Harris) Centre for Transplantation and Renal Research, Westmead Millennium Institute, University of Sydney, Australia (Johnson) Centrefor Kidney Disease Research, University of Queensland, Princess Alexandra Hospital, Brisbane, Australiaen
dc.description.addressM.G. Wong, Department of Renal Medicine, Royal North Shore Hospital, Sydney Medical School, Australiaen
dc.description.publicationstatusCONFERENCE ABSTRACTen
local.date.conferenceend2013-09-11en
dc.rights.statementCopyright 2014 Elsevier B.V., All rights reserved.en
dc.identifier.affiliationext(Wong, Pollock, Cooper, Kesselhut) Department of Renal Medicine, Royal North Shore Hospital, Sydney Medical School, Australia-
dc.identifier.affiliationext(Collins) Department of Medicine, University of Auckland, Auckland City Hospital, New Zealand-
dc.identifier.affiliationext(Craig) Department of Nephrology, Children's Hospital at Westmead, Sydney School of Public Health, Australia-
dc.identifier.affiliationext(Pilmore) School of Health and Social Development, Deakin University, Australia-
dc.identifier.affiliationext(Harris) Centre for Transplantation and Renal Research, Westmead Millennium Institute, University of Sydney, Australia-
dc.identifier.affiliationext(Johnson) Centrefor Kidney Disease Research, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia-
dc.identifier.affiliationmh(Branley) Monash Medical Centre and Eastern Health Renal Units, Australia-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeConference Abstract-
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