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https://repository.monashhealth.org/monashhealthjspui/handle/1/29137| Title: | Standardised neonatal parenteral nutrition formulations-Australasian neonatal parenteral nutrition consensus update 2017. | Authors: | Simmer K.;McIntosh J.;Josza E.;Opie G.;Downe L.;Andersen C.;Bhatia V.;Kumar P.;Malinen K.;Birch P.;Trivedi A.;McLeod G.;Quader S.;Rajadurai V.S.;Hewson M.P.;Nair A.;Williams M. ;Xiao J.;Ravindranathan H.;Broadbent R.;Lui K.;Bolisetty S.;Osborn D.;Schindler T.;Sinn J.;Deshpande G.;Wong C.S.;Jacobs S.E.;Phad N.;Pharande P.;Tobiansky R.;Luig M. | Monash Health Department(s): | Paediatric - Neonatal (Monash Newborn) | Institution: | (Bolisetty, Josza) Royal Hospital for Women, Locked Bag 2000, Randwick, Sydney, NSW 2031, Australia (Bolisetty) Conjoint Lecturer, University of New South Wales, Sydney, Australia (Osborn) Royal Prince Alfred Hospital, Sydney, Australia (Osborn, Sinn) University of Sydney, Sydney, Australia (Schindler) Royal Hospital for Women, University of New South Wales, Sydney, Australia (Sinn) Royal North Shore Hospital, Sydney, Australia (Deshpande, Downe) Nepean Hospital, Sydney, Australia (Wong) Hospital Kuala Lumpur, Kuala Lumpur, Malaysia (Jacobs) Deputy Clinical Director and Neonatal Paediatrician, Royal Women's Hospital, Parkville, VIC, Australia (Phad, McIntosh) John Hunter Children's Hospital, Newcastle, Australia (Pharande, Williams) Monash Children's Hospital, Clayton, VIC, Australia (Tobiansky) Liverpool Hospital, Sydney, Australia (Luig) Westmead Hospital, Sydney, Australia (Trivedi) Children's Hospital at Westmead, Sydney, Australia (Opie) Head and Neonatal Paediatrician, Mercy Hospital for Women, Heidelberg, VIC, Australia (Andersen, Bhatia) Head of Neonatology, Women's and Children's Hospital, North Adelaide, Australia (Kumar) Townsville Hospital, Townsville, Australia (Malinen) PGCert Clinical Education, PGDip Child Health (Associate), Advanced Pharmacist, Townsville Hospital, Townsville, Australia (Birch) Gold Coast University Hospital, Southport, Australia (Simmer) King Edward Memorial Hospital for Women, Subiaco, Australia (McLeod) King Edward Memorial and Princess Margaret Hospitals, Subiaco, Australia (Quader) Sydney Children's Hospital Network, Sydney, Australia (Rajadurai) Department of Neonatology, Kk Women's and Children's Hospital, Kampong Java, Singapore (Hewson) Wellington Hospital, Wellington South, New Zealand (Nair) Waikato Hospital, Hamilton, New Zealand (Xiao) Nepean Hospital, Penrith, Australia (Ravindranathan) Paediatric Intensivist, Sydney Children's Hospital, Sydney, Australia (Broadbent) Dunedin School of Medicine, Dunedin, New Zealand (Lui) University of New South Wales, Sydney, Australia | Issue Date: | 19-Aug-2020 | Copyright year: | 2020 | Publisher: | BioMed Central (E-mail: info@biomedcentral.com) | Place of publication: | United Kingdom | Publication information: | BMC Pediatrics. 20 (1) (no pagination), 2020. Article Number: 59. Date of Publication: 08 Feb 2020. | Journal: | BMC Pediatrics | Abstract: | Background: The first consensus standardised neonatal parenteral nutrition formulations were implemented in many neonatal units in Australia in 2012. The current update involving 49 units from Australia, New Zealand, Singapore, Malaysia and India was conducted between September 2015 and December 2017 with the aim to review and update the 2012 formulations and guidelines. Method(s): A systematic review of available evidence for each parenteral nutrient was undertaken and new standardised formulations and guidelines were developed. Result(s): Five existing preterm Amino acid-Dextrose formulations have been modified and two new concentrated Amino acid-Dextrose formulations added to optimise amino acid and nutrient intake according to gestation. Organic phosphate has replaced inorganic phosphate allowing for an increase in calcium and phosphate content, and acetate reduced. Lipid emulsions are unchanged, with both SMOFlipid (Fresenius Kabi, Australia) and ClinOleic (Baxter Healthcare, Australia) preparations included. The physicochemical compatibility and stability of all formulations have been tested and confirmed. Guidelines to standardise the parenteral nutrition clinical practice across facilities have also been developed. Conclusion(s): The 2017 PN formulations and guidelines developed by the 2017 Neonatal Parenteral Nutrition Consensus Group offer concise and practical instructions to clinicians on how to implement current and up-to-date evidence based PN to the NICU population.Copyright © 2020 The Author(s). | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1186/s12887-020-1958-9 | PubMed URL: | 32035481 [http://www.ncbi.nlm.nih.gov/pubmed/?term=32035481] | ISSN: | 1471-2431 (electronic) | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/29137 | Type: | Article | Subjects: | chloride clinoleic heparin lipid emulsion magnesium organophosphate phosphate phosphorus potassium smoflipid sodium trace element cannula umbilical artery catheter central cannula peripheral cannula urea amino acid intake Australia biochemical analysis biocompatibility calcium intake caloric intake carbohydrate intake cholestasis/co clinical practice dietary reference intake drug formulation drug stability evidence based practice fat intake fluid intake gestational age hyperglycemia hypertriglyceridemia/co hypoalbuminemia/co hypoglycemia/co long term care magnesium intake neonatal intensive care unit newborn care nutrient intake osmolality parenteral nutrition physical chemistry potassium intake practice guideline prematurity safety sodium intake standardization therapy effect urea nitrogen blood level acetic acid amino acid mixture plus glucose calcium |
Type of Clinical Study or Trial: | Systematic review and/or meta-analysis |
| Appears in Collections: | Articles |
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