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DC Field | Value | Language |
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dc.contributor.author | Markman B. | en |
dc.contributor.author | Raghunath A. | en |
dc.contributor.author | Chandrasekara S.D. | en |
dc.contributor.author | Anthony S.N. | en |
dc.date.accessioned | 2021-05-14T09:50:43Z | en |
dc.date.available | 2021-05-14T09:50:43Z | en |
dc.date.copyright | 2020 | en |
dc.date.created | 20200707 | en |
dc.date.issued | 2020-07-07 | en |
dc.identifier.citation | Critical Reviews in Oncology/Hematology. 152 (no pagination), 2020. Article Number: 103012. Date of Publication: August 2020. | en |
dc.identifier.issn | 1040-8428 | en |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/29167 | en |
dc.description.abstract | Background: Chemotherapy-induced nausea and vomiting (CINV) is the most common non-haematological toxicity of chemotherapy. Method(s): A systematic review and meta-analysis comparing short course (1-2 days) with long course (3+ days) dexamethasone in preventing CINV was performed in accordance with the PRISMA statement. Result(s): 1535 articles were screened to identify the 11 studies included in the review. Nine studies of 1892 patients were included in meta-analysis. There was no significant difference in complete response of nausea and vomiting between a short or long course of dexamethasone (RR 0.98, 95 % CI 0.89-1.07, p = 0.58). There was a lower risk of adverse events with a short course of dexamethasone (RR 0.80, 95 % CI 0.64-0.99, p = 0.04). Conclusion(s): There was no significant difference between a short or long course of dexamethasone in preventing nausea or vomiting, but a short course was associated with fewer adverse effects. PROSPERO protocol: CRD42019133785Copyright © 2020 Elsevier B.V. | en |
dc.language | English | en |
dc.language | en | en |
dc.publisher | Elsevier Ireland Ltd | en |
dc.relation.ispartof | Critical Reviews in Oncology/Hematology | en |
dc.subject.mesh | chemotherapy induced nausea and vomiting | - |
dc.subject.mesh | colorectal cancer | - |
dc.subject.mesh | constipation | - |
dc.subject.mesh | drug use | - |
dc.subject.mesh | fatigue | - |
dc.subject.mesh | headache | - |
dc.subject.mesh | dexamethasone [Adverse Drug Reaction] | - |
dc.subject.mesh | dexamethasone | - |
dc.subject.mesh | granisetron | - |
dc.subject.mesh | irinotecan | - |
dc.subject.mesh | stomach cancer | - |
dc.subject.mesh | advanced cancer | - |
dc.subject.mesh | adverse event | - |
dc.subject.mesh | anorexia | - |
dc.title | Duration of dexamethasone administration for the prevention of chemotherapy-induced nausea and vomiting - a systematic review and meta-analysis. [Critical Reviews in Oncology/Hematology] | en |
dc.type | Review | en |
dc.type.studyortrial | Systematic review and/or meta-analysis | - |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1016/j.critrevonc.2020.103012 | - |
dc.publisher.place | Ireland | en |
dc.identifier.pubmedid | 32593142 [http://www.ncbi.nlm.nih.gov/pubmed/?term=32593142] | en |
dc.identifier.source | 2006830626 | en |
dc.identifier.institution | (Raghunath, Markman) Monash Health, Victoria, Australia (Chandrasekara) Alfred Health, Victoria, Australia (Anthony) Melbourne Health, Victoria, Australia (Markman) Monash University, Victoria, Australia | en |
dc.description.address | A. Raghunath, Monash Health, 246 Clayton Road, Clayton, VIC 3168, Australia. E-mail: ajraghunath@gmail.com | en |
dc.description.publicationstatus | Embase | en |
dc.rights.statement | Copyright 2020 Elsevier B.V., All rights reserved. | en |
dc.subect.keywords | Chemotherapy-induced nausea and vomiting Corticosteroids Dexamethasone Meta-analysis NK1 inhibitors Systematic review | en |
dc.identifier.authoremail | Raghunath A.; ajraghunath@gmail.com | en |
item.fulltext | No Fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | Review | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
crisitem.author.dept | Monash Doctors Workforce | - |
Appears in Collections: | Articles |
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