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Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/31875
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DC FieldValueLanguage
dc.contributor.authorYu V.Y.H.en
dc.contributor.authorWalker A.M.en
dc.contributor.authorFeng S.Y.S.en
dc.date.accessioned2021-05-14T10:47:26Zen
dc.date.available2021-05-14T10:47:26Zen
dc.date.copyright2007en
dc.date.created20070524en
dc.date.issued2012-10-16en
dc.identifier.citationHong Kong Journal of Paediatrics. 12 (2) (pp 111-117), 2007. Date of Publication: April 2007.en
dc.identifier.issn1013-9923en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/31875en
dc.description.abstractEndotoxin induces complex changes in the newborn cerebral circulation, including vasoconstriction by down-regulating endothelial nitric oxide synthase and stimulating the production of endothelin and cyclooxygenase-2 derived vasoconstrictors including thromboxane A2, while also promoting vasodilatation by increasing the expression of inducible nitric oxide synthase and cyclooxygenase-2 derived vasodilators. Together, these changes represent a complex dysregulation of the newborn cerebral circulation. This review considers the effects of neonatal endotoxaemia on cerebral circulatory changes and endothelium-derived factors, and their implications for cerebral circulatory control.en
dc.languageEnglishen
dc.languageenen
dc.publisherMedcom Limited (18 Cheung Lee Street, Chaiwan, Hong Kong)en
dc.titleEndotoxin-induced circulatory changes in the newborn brain: A review.en
dc.typeReviewen
dc.type.studyortrialReview article (e.g. literature review, narrative review)-
dc.publisher.placeHong Kongen
dc.identifier.source46663408en
dc.identifier.institution(Feng, Yu, Walker) Ritchie Centre for Baby Health Research, Monash Institute of Medical Research, Monash University, Clayton, Vic. 3168, Australia (Feng, Yu) Department of Pediatrics, Monash University, Monash Medical Centre, Clayton, Vic. 3168, Australiaen
dc.description.addressA.M. Walker, Ritchie Centre for Baby Health Research, Monash Institute of Medical Research, Monash University, Clayton, Vic. 3168, Australiaen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2012 Elsevier B.V., All rights reserved.en
dc.subect.keywordsCerebral blood flow Endothelium Endotoxin Newbornen
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeReview-
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