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Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/32786
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dc.contributor.authorMcDonald C.F.en
dc.contributor.authorBrodie G.N.en
dc.contributor.authorPretto J.J.en
dc.contributor.authorMacGregor D.P.en
dc.contributor.authorGoh N.S.L.en
dc.date.accessioned2021-05-14T11:06:54Zen
dc.date.available2021-05-14T11:06:54Zen
dc.date.copyright2003en
dc.date.created20030507en
dc.date.issued2012-10-19en
dc.identifier.citationRespirology. 8 (1) (pp 91-94), 2003. Date of Publication: March 2003.en
dc.identifier.issn1323-7799en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/32786en
dc.description.abstractLangerhans cell histiocytosis (LCH) is a rare disorder which frequently involves the lungs of affected adults. Recent evidence suggests it is a clonal neoplastic disorder. Prognosis in this disease is variable, but in its multisystem form or when associated with progressive respiratory dysfunction, prognosis is poor. Recent case reports and a phase II trial of the antimonocyte drug 2-chlorodeoxyadenosine (2CDA) have described success in treating LCH. We used 2CDA to treat a young Australian man with LCH involving lungs and bone. A complete symptomatic remission was achieved with no evidence of recurrence some 5 years after completion of chemotherapy.en
dc.languageenen
dc.languageEnglishen
dc.publisherBlackwell Publishing (550 Swanston Street, Carlton South VIC 3053, Australia)en
dc.titleSuccessful treatment of Langerhans cell histiocytosis with 2-chlorodeoxyadenosine.en
dc.typeArticleen
dc.type.studyortrialCase series or case report-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1046/j.1440-1843.2003.00427.xen
dc.publisher.placeJapanen
dc.identifier.pubmedid12856748 [http://www.ncbi.nlm.nih.gov/pubmed/?term=12856748]en
dc.identifier.source36504287en
dc.identifier.institution(Goh) Royal Brompton Hospital, London, United Kingdom (McDonald, Pretto) Department of Respiratory Medicine, Austin and Repatriation Med. Centre, Heidelberg, Vic., Australia (MacGregor) Department of Anatomical Pathology, Austin and Repatriation Med. Centre, Heidelberg, Vic., Australia (Brodie) Department of Medical Oncology, Monash Medical Centre, Clayton, Vic., Australia (McDonald) Department of Respiratory Medicine, HSB, Austin and Repatriation Med. Centre, Studley Road, Heidelberg, Vic. 3084, Australiaen
dc.description.addressC.F. McDonald, Department of Respiratory Medicine, HSB, Austin and Repatriation Med. Centre, Studley Road, Heidelberg, Vic. 3084, Australia. E-mail: christine.mcdonald@armc.org.auen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2012 Elsevier B.V., All rights reserved.en
dc.subect.keywords2-chlorodeoxy-adenosine Langerhans cell histiocytosis Pulmonary histiocytosisen
dc.identifier.authoremailMcDonald C.F.; christine.mcdonald@armc.org.auen
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeArticle-
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