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DC Field | Value | Language |
---|---|---|
dc.contributor.author | McDonald C.F. | en |
dc.contributor.author | Brodie G.N. | en |
dc.contributor.author | Pretto J.J. | en |
dc.contributor.author | MacGregor D.P. | en |
dc.contributor.author | Goh N.S.L. | en |
dc.date.accessioned | 2021-05-14T11:06:54Z | en |
dc.date.available | 2021-05-14T11:06:54Z | en |
dc.date.copyright | 2003 | en |
dc.date.created | 20030507 | en |
dc.date.issued | 2012-10-19 | en |
dc.identifier.citation | Respirology. 8 (1) (pp 91-94), 2003. Date of Publication: March 2003. | en |
dc.identifier.issn | 1323-7799 | en |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/32786 | en |
dc.description.abstract | Langerhans cell histiocytosis (LCH) is a rare disorder which frequently involves the lungs of affected adults. Recent evidence suggests it is a clonal neoplastic disorder. Prognosis in this disease is variable, but in its multisystem form or when associated with progressive respiratory dysfunction, prognosis is poor. Recent case reports and a phase II trial of the antimonocyte drug 2-chlorodeoxyadenosine (2CDA) have described success in treating LCH. We used 2CDA to treat a young Australian man with LCH involving lungs and bone. A complete symptomatic remission was achieved with no evidence of recurrence some 5 years after completion of chemotherapy. | en |
dc.language | en | en |
dc.language | English | en |
dc.publisher | Blackwell Publishing (550 Swanston Street, Carlton South VIC 3053, Australia) | en |
dc.title | Successful treatment of Langerhans cell histiocytosis with 2-chlorodeoxyadenosine. | en |
dc.type | Article | en |
dc.type.studyortrial | Case series or case report | - |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1046/j.1440-1843.2003.00427.x | en |
dc.publisher.place | Japan | en |
dc.identifier.pubmedid | 12856748 [http://www.ncbi.nlm.nih.gov/pubmed/?term=12856748] | en |
dc.identifier.source | 36504287 | en |
dc.identifier.institution | (Goh) Royal Brompton Hospital, London, United Kingdom (McDonald, Pretto) Department of Respiratory Medicine, Austin and Repatriation Med. Centre, Heidelberg, Vic., Australia (MacGregor) Department of Anatomical Pathology, Austin and Repatriation Med. Centre, Heidelberg, Vic., Australia (Brodie) Department of Medical Oncology, Monash Medical Centre, Clayton, Vic., Australia (McDonald) Department of Respiratory Medicine, HSB, Austin and Repatriation Med. Centre, Studley Road, Heidelberg, Vic. 3084, Australia | en |
dc.description.address | C.F. McDonald, Department of Respiratory Medicine, HSB, Austin and Repatriation Med. Centre, Studley Road, Heidelberg, Vic. 3084, Australia. E-mail: christine.mcdonald@armc.org.au | en |
dc.description.publicationstatus | Embase | en |
dc.rights.statement | Copyright 2012 Elsevier B.V., All rights reserved. | en |
dc.subect.keywords | 2-chlorodeoxy-adenosine Langerhans cell histiocytosis Pulmonary histiocytosis | en |
dc.identifier.authoremail | McDonald C.F.; christine.mcdonald@armc.org.au | en |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | Article | - |
Appears in Collections: | Articles |
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