Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/34064
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dc.contributor.authorLan H.Y.en
dc.contributor.authorNikolic-Paterson D.J.en
dc.contributor.authorAtkins R.C.en
dc.date.accessioned2021-05-14T11:31:48Zen
dc.date.available2021-05-14T11:31:48Zen
dc.date.copyright1996en
dc.date.created19961210en
dc.date.issued2012-10-22en
dc.identifier.citationSeminars in Nephrology. 16 (6) (pp 583-590), 1996. Date of Publication: 1996.en
dc.identifier.issn0270-9295en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/34064en
dc.description.abstractInterleukin-1 (IL-1) is a pro-inflammatory cytokine that exerts a wide range of biological effects. The recently identified IL-1 receptor antagonist (IL-1ra) has provided a tool for blocking IL-1 activity in vivo, leading to a detailed understanding of the role of this cytokine in the inflammatory response. The importance of IL-1 production in glomerulonephritis has been shown by the ability of IL-1ra treatment to suppress the induction and progression of experimental crescentic glomerulonephritis. Although further studies are required, IL-1ra treatment is an attractive adjunct therapy for patients with progressive glomerulonephritis.en
dc.languageenen
dc.languageEnglishen
dc.publisherW.B. Saunders (Independence Square West, Philadelphia PA 19106-3399, United States)en
dc.titleInterleukin-1 receptor antagonism.en
dc.typeReviewen
dc.type.studyortrialReview article (e.g. literature review, narrative review)-
dc.publisher.placeUnited Statesen
dc.identifier.pubmedid9125803 [http://www.ncbi.nlm.nih.gov/pubmed/?term=9125803]en
dc.identifier.source26395522en
dc.identifier.institution(Nikolic-Paterson) Department of Nephrology, Monash Medical Centre, Clayton, Vic. 3168, Australia (Lan, Atkins) Director of Nephrology, Monash Medical Centre, 246 Clayton Rd, Clayton, Vic. 3168, Australiaen
dc.description.addressR.C. Atkins, Monash Medical Centre, 246 Clayton Rd, Clayton, Vic. 3168, Australiaen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2012 Elsevier B.V., All rights reserved.en
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeReview-
crisitem.author.deptNephrology-
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