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Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/34283
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dc.contributor.authorDixey J.en
dc.contributor.authorGoulding N.J.en
dc.contributor.authorMitra D.en
dc.contributor.authorMorand, Ericen
dc.contributor.authorJefferiss C.M.en
dc.date.accessioned2021-05-14T11:35:44Zen
dc.date.available2021-05-14T11:35:44Zen
dc.date.copyright1994en
dc.date.created19940314en
dc.date.issued2012-10-25en
dc.identifier.citationArthritis and Rheumatism. 37 (2) (pp 207-211), 1994. Date of Publication: February 1994.en
dc.identifier.issn0004-3591en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/34283en
dc.description.abstractObjective. To investigate leukocyte lipocortin-1 production in rheumatoid arthritis (RA). Methods. Eight control and 8 RA subjects received 100 mg hydrocortisone intravenously. Leukocyte lipocortin-1 was measured by enzyme- linked immunosorbent assay. Results. Hydrocortisone induced significant increases in lipocortin-1 production by control mononuclear cells (MNC) (P = 0.006 versus baseline) but not by RA MNC (P = 0.44 versus baseline). Peak lipocortin-1 levels in control MNC were significantly higher than those in RA MNC (P = 0.014). Conclusion. These results indicate that glucocorticoid- induced MNC lipocortin-1 production is impaired in RA.en
dc.languageEnglishen
dc.languageenen
dc.publisherJohn Wiley and Sons Inc. (P.O.Box 18667, Newark NJ 07191-8667, United States)en
dc.titleImpaired glucocorticoid induction of mononuclear leukocyte lipocortin-1 in rheumatoid arthritis.en
dc.typeArticleen
dc.identifier.affiliationRheumatology-
dc.publisher.placeUnited Statesen
dc.identifier.pubmedid8129776 [http://www.ncbi.nlm.nih.gov/pubmed/?term=8129776]en
dc.identifier.source24065495en
dc.identifier.institution(Morand, Jefferiss, Dixey, Mitra, Goulding) Inflammation Research Group, Bath Inst. for Rheumatic Diseases, Trim Bridge, Bath, United Kingdom (Morand) Monash Rheumatology Unit, Monash Medical Centre, Locked Bag No. 29, Clayton, Vic. 3168, Australiaen
dc.description.addressE.F. Morand, Monash Rheumatology Unit, Monash Medical Centre, Clayton, Vic. 3168, Australiaen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2012 Elsevier B.V., All rights reserved.en
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeArticle-
crisitem.author.deptRheumatology-
crisitem.author.deptCentre for Inflammatory Diseases at Monash Health-
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