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Title: | Elevated maternal plasma immunoreactive phospholipase A2 in human preterm and term labour. | Authors: | Smith G.M.;Brennecke S.P.;Scott K.F.;Bishop G.J.;Rajkovic I.A.;Rice G.E. | Institution: | (Rice, Brennecke, Scott, Smith, Rajkovic, Bishop) Monash Perinatal Unit, Monash Univ., Department of Obstetrics/Gynaecology, Monash Medical Centre, 246 Clayton Road, Clayton, Vic. 3168, Australia | Issue Date: | 25-Oct-2012 | Copyright year: | 1992 | Publisher: | Springer Verlag (Tiergartenstrasse 17, Heidelberg D-69121, Germany) | Place of publication: | Germany | Publication information: | Eicosanoids. 5 (1) (pp 9-12), 1992. Date of Publication: 1992. | Abstract: | Peripheral plasma concentrations of immunoreactive phospholipase A2 (irPLA2) (Type II, non-pancreatic) were determined in 110 women during pregnancy. The concentration of irPLA2 did not significantly change during pregnancy (5.7 +/- 0.6 ng/ml, n = 72) until the onset of labour. When compared with non-labouring women, irPLA2 concentrations were significantly elevated in association with both preterm labour (13.3 +/- 2.4 ng/ml, n = 15, p < 0.02) and labour at term (10.4 +/- 1.7, n = 23, p < 0.02). These data suggest that maternal plasma irPLA2 may be reflective of the mechanism(s) underlying the labour-associated increase in human gestational tissue eicosanoid formation. | PubMed URL: | 1419083 [http://www.ncbi.nlm.nih.gov/pubmed/?term=1419083] | ISSN: | 0934-9820 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/34496 | Type: | Article |
Appears in Collections: | Articles |
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