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Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lu A.B. | en |
dc.contributor.author | Rolnik D.L. | en |
dc.contributor.author | Lazarus B. | en |
dc.contributor.author | Palmer, Kirsten R. | en |
dc.date.accessioned | 2021-05-14T12:00:16Z | en |
dc.date.available | 2021-05-14T12:00:16Z | en |
dc.date.copyright | 2019 | en |
dc.date.created | 20200529 | en |
dc.date.issued | 2020-05-29 | en |
dc.identifier.citation | Obstetrics and gynecology. 134 (6) (pp 1215-1218), 2019. Date of Publication: 01 Dec 2019. | en |
dc.identifier.issn | 1873-233X (electronic) | en |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/35522 | en |
dc.description.abstract | BACKGROUND: Untreated microangiopathic hemolytic anemia in pregnancy is associated with adverse maternal and perinatal outcomes. Accurate diagnosis is challenging owing to nonspecific clinical features and pathologic findings. Timely initiation of appropriate management is essential to optimize maternal and perinatal outcomes. CASE: A 26-year-old primiparous woman presented at 20 weeks of gestation with new-onset microangiopathic hemolytic anemia on a background of poorly controlled type 1 diabetes. She received eculizumab for presumed atypical hemolytic uremic syndrome. At 24 weeks of gestation, she developed superimposed early-onset preeclampsia; she delivered at 27 weeks of gestation after continuing eculizumab. CONCLUSION(S): Eculizumab may prolong pregnancy in early-onset preeclampsia. Additional research is needed to assess short-term and long-term maternal and newborn outcomes. | en |
dc.language | English | en |
dc.language | en | en |
dc.publisher | NLM (Medline) | en |
dc.relation.ispartof | Obstetrics and Gynecology | - |
dc.subject.mesh | eculizumab | - |
dc.subject.mesh | monoclonal antibody/ad | - |
dc.subject.mesh | monoclonal antibody | - |
dc.subject.mesh | preeclampsia | - |
dc.subject.mesh | diabetes mellitus | - |
dc.subject.mesh | differential | - |
dc.subject.mesh | hemolytic uremic syndrome | - |
dc.subject.mesh | hemolytic uremic syndrome | - |
dc.subject.mesh | preeclampsia | - |
dc.subject.mesh | pregnancy | - |
dc.subject.mesh | prenatal | - |
dc.subject.mesh | prolonged pregnancy | - |
dc.subject.mesh | second trimester pregnancy | - |
dc.title | Pregnancy Prolongation After Eculizumab Use in Early-Onset Preeclampsia. | en |
dc.type | Article | en |
dc.identifier.affiliation | Obstetrics and Gynaecology (Monash Women's) | - |
dc.identifier.affiliation | Nephrology | - |
dc.type.studyortrial | Case series or case report | - |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1097/AOG.0000000000003570 | - |
dc.publisher.place | United States | en |
dc.identifier.pubmedid | 31764731 [http://www.ncbi.nlm.nih.gov/pubmed/?term=31764731] | en |
dc.identifier.source | 629958356 | en |
dc.identifier.institution | (Lu) Departments of Obstetrics & Gynecology and Nephrology, Monash Health, VIC, Australia | en |
dc.rights.statement | This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine | en |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Obstetrics and Gynaecology (Monash Women's) | - |
crisitem.author.dept | Obstetrics and Gynaecology (Monash Women's) | - |
Appears in Collections: | Articles |
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