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https://repository.monashhealth.org/monashhealthjspui/handle/1/38499| Title: | Treatment Options for Resistant Kawasaki Disease. | Authors: | Burgner D.;Phuong L.K.;Gowdie P. ;Curtis N.;Akikusa J. | Institution: | (Phuong, Curtis) Infectious Diseases Unit, Royal Children's Hospital Melbourne, Parkville, Australia (Curtis, Burgner) Department of Paediatrics, The University of Melbourne, Parkville, Australia (Gowdie, Akikusa) Rheumatology Service, Department of General Medicine, Royal Children's Hospital, Melbourne, Australia (Gowdie) Department of Paediatrics and Department of Paediatric Rheumatology, Monash Children's Hospital, Clayton, Australia (Gowdie, Burgner) Department of Paediatrics, Monash University, Melbourne, Australia (Akikusa, Burgner) Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Flemington Road, Parkville, VIC 3052, Australia | Issue Date: | 30-Jan-2018 | Copyright year: | 2018 | Publisher: | Springer International Publishing | Place of publication: | Switzerland | Publication information: | Pediatric Drugs. 20 (1) (pp 59-80), 2018. Date of Publication: 01 Feb 2018. | Journal: | Pediatric Drugs | Abstract: | "Resistant" Kawasaki disease is defined by the American Heart Association as failure to respond within 36 h following the first dose of intravenous immunoglobulin. The optimal management of resistant Kawasaki disease remains uncertain, the outcomes are potentially serious, and the cost of some treatments is considerable. We review the current evidence to guide treatment of resistant Kawasaki disease. Given the relative rarity, there are few trial data, and studies tend to be small and methodologically heterogeneous, making interpretation difficult and limiting generalisability. The literature on resistant Kawasaki disease should be interpreted with reference to current expert consensus guidelines.Copyright © 2017, Springer International Publishing AG. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1007/s40272-017-0269-6 | ORCID: | Burgner, David; ORCID: http://orcid.org/0000-0002-8304-4302 | PubMed URL: | 29101553 [http://www.ncbi.nlm.nih.gov/pubmed/?term=29101553] | ISSN: | 1174-5878 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/38499 | Type: | Review | Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
| Appears in Collections: | Articles |
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