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Title: | Distant spread of a supratentorial glioblastoma to the spinal cord. | Authors: | Ravindran K.;Lasocki A.;Gaillard F. | Institution: | (Ravindran, Gaillard) Department of Radiology, The Royal Melbourne Hospital, Parkville, VIC, Australia (Gaillard) Department of Radiology, The University of Melbourne, Parkville, VIC, Australia (Lasocki) Department of Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia (Lasocki) Monash Imaging, Monash Health, Clayton, VIC, Australia | Issue Date: | 27-Mar-2017 | Copyright year: | 2017 | Publisher: | Churchill Livingstone | Place of publication: | United Kingdom | Publication information: | Journal of Clinical Neuroscience. 38 (pp 56-57), 2017. Date of Publication: 01 Apr 2017. | Journal: | Journal of Clinical Neuroscience | Abstract: | Extracranial spread from a glioblastoma is rare. We present a case of a 48 year-old man with a previously radiologically-stable left temporal lobe glioblastoma presenting with symptoms referrable to the spinal cord. MRI revealed a spinal cord lesion, with the differential including transverse myelitis and tumour. Open surgical biopsy revealed high-grade astrocytoma. Genetic analysis of both the supratentorial and spinal tumours revealed R132H IDH1 mutations, providing evidence that the spinal cord lesion had spread from the supratentorial tumour.Copyright © 2016 | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1016/j.jocn.2016.11.010 | PubMed URL: | 28089418 [http://www.ncbi.nlm.nih.gov/pubmed/?term=28089418] | ISSN: | 0967-5868 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/39496 | Type: | Article | Type of Clinical Study or Trial: | Case series or case report |
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