Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/49891
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dc.contributor.authorLu C.-
dc.contributor.authorKitching A.R.-
dc.date.accessioned2023-06-26T06:04:40Z-
dc.date.available2023-06-26T06:04:40Z-
dc.date.copyright2023-
dc.date.issued2023-06-15en
dc.identifier.citationKidney International. 104(1) (pp 28-31), 2023. Date of Publication: July 2023.-
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/49891-
dc.description.abstractCD4+ T cells that express forkhead box protein 3 are important in maintaining tolerance and restraining effector responses. Herrnstadt et al. use a model of rapidly progressive glomerulonephritis to examine the nature and role of forkhead box protein 3-positive and retinoid acid-related orphan receptor gammat-positive regulatory T cells. These cells are prominent in experimental glomerulonephritis, both locally and systemically, and are present in kidneys of people with anti-neutrophil cytoplasmic antibody-associated vasculitis. Functionally, despite their expression of retinoid acid-related orphan receptor gammat, associated with T-helper cell 17 cells, they regulate cellular immunity, both systemically and within the kidney.Copyright © 2023 International Society of Nephrology-
dc.publisherElsevier B.V.-
dc.relation.ispartofKidney International-
dc.subject.meshANCA associated vasculitis-
dc.subject.meshCD4+ T lymphocyte-
dc.subject.meshexperimental glomerulonephritis-
dc.subject.meshgene expression-
dc.subject.meshglomerulonephritis-
dc.subject.meshhelper cell-
dc.subject.meshimmunoregulation-
dc.subject.meshprotein expression-
dc.subject.meshprotein function-
dc.subject.meshrapidly progressive glomerulonephritis-
dc.subject.meshregulatory T lymphocyte-
dc.subject.meshforkhead transcription factor-
dc.subject.meshretinoic acid-
dc.titleRORing toward immunoregulation in glomerulonephritis?-
dc.typeNote-
dc.identifier.affiliationCentre for Inflammatory Diseases at Monash Health-
dc.identifier.affiliationNephrology-
dc.identifier.affiliationPaediatric - Nephrology-
dc.type.studyortrialOpinion, perspective or news-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1016/j.kint.2023.04.018-
dc.publisher.placeNetherlands-
dc.identifier.institution(Lu, Kitching) Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Monash University, Clayton, VIC, Australia-
dc.identifier.institution(Kitching) Department of Nephrology, Monash Health, Clayton, VIC, Australia-
dc.identifier.institution(Kitching) Department of Pediatric Nephrology, Monash Health, Clayton, Victoria, Australia-
dc.description.grantNo: 2008921 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia-
dc.identifier.affiliationmh(Lu, Kitching) Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Monash University, Clayton, VIC, Australia-
dc.identifier.affiliationmh(Kitching) Department of Nephrology, Monash Health, Clayton, VIC, Australia-
dc.identifier.affiliationmh(Kitching) Department of Pediatric Nephrology, Monash Health, Clayton, Victoria, Australia-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairetypeNote-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptNephrology-
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