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DC Field | Value | Language |
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dc.contributor.author | Lu C. | - |
dc.contributor.author | Kitching A.R. | - |
dc.date.accessioned | 2023-06-26T06:04:40Z | - |
dc.date.available | 2023-06-26T06:04:40Z | - |
dc.date.copyright | 2023 | - |
dc.date.issued | 2023-06-15 | en |
dc.identifier.citation | Kidney International. 104(1) (pp 28-31), 2023. Date of Publication: July 2023. | - |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/49891 | - |
dc.description.abstract | CD4+ T cells that express forkhead box protein 3 are important in maintaining tolerance and restraining effector responses. Herrnstadt et al. use a model of rapidly progressive glomerulonephritis to examine the nature and role of forkhead box protein 3-positive and retinoid acid-related orphan receptor gammat-positive regulatory T cells. These cells are prominent in experimental glomerulonephritis, both locally and systemically, and are present in kidneys of people with anti-neutrophil cytoplasmic antibody-associated vasculitis. Functionally, despite their expression of retinoid acid-related orphan receptor gammat, associated with T-helper cell 17 cells, they regulate cellular immunity, both systemically and within the kidney.Copyright © 2023 International Society of Nephrology | - |
dc.publisher | Elsevier B.V. | - |
dc.relation.ispartof | Kidney International | - |
dc.subject.mesh | ANCA associated vasculitis | - |
dc.subject.mesh | CD4+ T lymphocyte | - |
dc.subject.mesh | experimental glomerulonephritis | - |
dc.subject.mesh | gene expression | - |
dc.subject.mesh | glomerulonephritis | - |
dc.subject.mesh | helper cell | - |
dc.subject.mesh | immunoregulation | - |
dc.subject.mesh | protein expression | - |
dc.subject.mesh | protein function | - |
dc.subject.mesh | rapidly progressive glomerulonephritis | - |
dc.subject.mesh | regulatory T lymphocyte | - |
dc.subject.mesh | forkhead transcription factor | - |
dc.subject.mesh | retinoic acid | - |
dc.title | RORing toward immunoregulation in glomerulonephritis? | - |
dc.type | Note | - |
dc.identifier.affiliation | Centre for Inflammatory Diseases at Monash Health | - |
dc.identifier.affiliation | Nephrology | - |
dc.identifier.affiliation | Paediatric - Nephrology | - |
dc.type.studyortrial | Opinion, perspective or news | - |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1016/j.kint.2023.04.018 | - |
dc.publisher.place | Netherlands | - |
dc.identifier.institution | (Lu, Kitching) Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Monash University, Clayton, VIC, Australia | - |
dc.identifier.institution | (Kitching) Department of Nephrology, Monash Health, Clayton, VIC, Australia | - |
dc.identifier.institution | (Kitching) Department of Pediatric Nephrology, Monash Health, Clayton, Victoria, Australia | - |
dc.description.grant | No: 2008921 Organization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia | - |
dc.identifier.affiliationmh | (Lu, Kitching) Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Monash University, Clayton, VIC, Australia | - |
dc.identifier.affiliationmh | (Kitching) Department of Nephrology, Monash Health, Clayton, VIC, Australia | - |
dc.identifier.affiliationmh | (Kitching) Department of Pediatric Nephrology, Monash Health, Clayton, Victoria, Australia | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.openairetype | Note | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Nephrology | - |
Appears in Collections: | Articles |
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