Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/51485
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dc.contributor.authorPeters R.L.-
dc.contributor.authorSoriano V.X.-
dc.contributor.authorAllen K.J.-
dc.contributor.authorTang M.L.K.-
dc.contributor.authorPerrett K.P.-
dc.contributor.authorLowe A.J.-
dc.contributor.authorWijesuriya R.-
dc.contributor.authorParker K.M.-
dc.contributor.authorLoke P.-
dc.contributor.authorDharmage S.C.-
dc.contributor.authorKoplin J.J.-
dc.date.accessioned2024-04-18T06:10:57Z-
dc.date.available2024-04-18T06:10:57Z-
dc.date.copyright2024-
dc.date.issued2024-04-11en
dc.identifier.citationJournal of Allergy and Clinical Immunology: In Practice. (no pagination), 2024. Date of Publication: 2024.-
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/51485-
dc.description.abstractBackground: There are limited longitudinal data on the population prevalence of allergic conditions during childhood, and few studies have incorporated the reference standard oral food challenge to confirm food allergy. Objective(s): To describe the population prevalence of IgE-mediated food allergy, eczema, asthma, and rhinitis at ages 6 and 10 years in Melbourne, Australia. Method(s): The HealthNuts study recruited 5,276 1-year-old infants in Melbourne, Australia, with repeat assessments at ages 6 and 10 years. At ages 6 and 10 years, carers completed a questionnaire on symptoms and doctor diagnosis of allergic conditions (International Study of Asthma and Allergies in Children). Children were invited to attend a clinic assessment including skin prick test, lung function tests, and oral food challenges when indicated. To minimize the impact of attrition bias, prevalence estimates among participants at ages 6 and 10 years were weighted to reflect characteristics of the whole cohort at recruitment. Result(s): In total, 4,455 and 4,065 families participated at ages 6 and 10 years, respectively (84% and 77% of the original cohort). Of those, 73% and 55% of participants ages 6 and 10 years, respectively, completed clinical assessments. Overall, 36.5% (95% CI, 34.8-38.2) and 38.2% (95% CI, 36.5-40.1%) of 6- and 10-year-olds had at least one current allergic disease, and around one third of those had two or more allergic diseases. Food allergy occurred in 6.4% (95% CI, 5.6-7.2) of 6-year olds and 6.3% (95% CI, 5.5-7.2) of 10-year-olds. Among infants with challenge-confirmed food allergy in infancy, 45% had persistent disease at age 10 years. The prevalence of current diagnosed asthma at ages 6 and 10 years were 12.1% (95% CI, 10.9-13.3) and 13.1% (95% CI, 11.9-14.4), respectively, current eczema decreased slightly from 15.3% (95% CI, 14.1-19.7) at age 6 years to 12.9% (95% CI, 11.7-14.2) at age 10 years, and current rhinitis increased from 15.1% (95% CI, 13.9-16.5) at age 6 years to 25.0% (95% CI, 23.4-26.7) at age 10 years. Conclusion(s): Allergic diseases affect 40% of primary school-age children; one third have multiple allergic diagnoses. Challenge-confirmed food allergy prevalence remains high, and 45% of infants with food allergy have persistent disease to age 10 years.Copyright © 2024 American Academy of Allergy, Asthma & Immunology-
dc.publisherAmerican Academy of Allergy, Asthma and Immunology-
dc.relation.ispartofJournal of Allergy and Clinical Immunology: In Practice-
dc.subject.meshallergic asthma-
dc.subject.mesheczema-
dc.subject.meshepidemiology-
dc.subject.meshfood allergy-
dc.subject.meshIgE mediated food allergy-
dc.subject.meshlung function test-
dc.subject.meshrhinitis-
dc.titleThe prevalence of IGE-mediated food allergy and other allergic diseases in the first 10 years: the population-based, longitudinal healthnuts study.-
dc.typeArticle-
dc.identifier.affiliationPaediatric - Infection and Immunity-
dc.type.studyortrialObservational study (cohort, case-control, cross sectional, or survey)-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1016/j.jaip.2024.03.015-
dc.publisher.placeUnited States-
dc.identifier.institution(Peters, Soriano, Allen, Tang, Perrett, Lowe, Wijesuriya, Parker, Loke, Dharmage, Koplin) Murdoch Children's Research Institute, Parkville, VIC, Australia-
dc.identifier.institution(Peters, Soriano, Tang, Perrett, Wijesuriya, Parker, Loke) Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia-
dc.identifier.institution(Tang, Perrett) Department of Allergy and Immunology, Royal Children's Hospital, Parkville, VIC, Australia-
dc.identifier.institution(Lowe, Dharmage) Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia-
dc.identifier.institution(Loke) Monash Children's Hospital, Monash Health, Clayton, VIC, Australia-
dc.identifier.institution(Koplin) Child Health Research Centre, University of Queensland, Brisbane, QLD, Australia-
dc.description.grantOrganization: (DBV) *De Blindas Vanner* Organization No: 501100011831 Country: Sweden-
dc.description.grantOrganization: (GSK) *GlaxoSmithKline* Organization No: 100004330 Country: United Kingdom-
dc.description.grantOrganization: (NHMRC) *National Health and Medical Research Council* Organization No: 501100000925 Country: Australia-
dc.description.grantOrganization: *AstraZeneca* Organization No: 100004325 Country: United Kingdom-
dc.description.grantOrganization: *Ilhan Food Allergy Foundation* Organization No: 501100003842 Country: Australia-
dc.description.grantOrganization: *Medical Research Foundation* Organization No: 501100009187 Country: United Kingdom-
dc.description.grantOrganization: *Novartis* Organization No: 100004336 Country: Switzerland-
dc.description.grantOrganization: *Sanofi* Organization No: 100004339 Country: United States-
dc.identifier.affiliationmh(Loke) Monash Children's Hospital, Monash Health, Clayton, VIC, Australia-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
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