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DC Field | Value | Language |
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dc.contributor.author | Trigueira P.D.C. | - |
dc.contributor.author | Leal V.D.O. | - |
dc.contributor.author | Cardoso B.R. | - |
dc.contributor.author | Mafra D. | - |
dc.contributor.author | Araujo M.C. | - |
dc.contributor.author | Stockler-Pinto M.B. | - |
dc.date.accessioned | 2024-10-16T01:56:31Z | - |
dc.date.available | 2024-10-16T01:56:31Z | - |
dc.date.copyright | 2024 | - |
dc.date.issued | 2024-10-04 | en |
dc.identifier.citation | Nutrition Research Reviews. (no pagination), 2024. Date of Publication: 2024. | - |
dc.identifier.uri | https://repository.monashhealth.org/monashhealthjspui/handle/1/52598 | - |
dc.description.abstract | Selenium (Se) is a mineral with several biological functions, and studies have shown that its deficiency can be linked to many complications in patients with chronic kidney disease (CKD). This study aims to systematically review the effects of Se supplementation in patients with CKD undergoing haemodialysis (HD). This systematic review was carried out according to the PRISMA statement. Clinical trials were searched in PubMed, Lilacs, Embase, Scopus and Cochrane Library databases from inception to July 2021 and updated in July 2024. The protocol was registered on PROSPERO (CRD42021231444). Two independent reviewers performed the study screening and data extraction, and the risk of bias was evaluated using the Cochrane Collaboration tool. Thirteen studies were included in this review. Only nine studies showed results on Se levels; in all, reduced Se levels were observed before supplementation. A positive effect of supplementation on plasma Se level was demonstrated. Of the ten studies analysed, six demonstrated positive effects on antioxidant and inflammatory markers. Only one study analysed immunological parameters, showing a positive impact. From two studies that analysed thyroid hormones, only one showed positive results. All studies were classified as high risk of bias. The findings suggest that Se supplementation significantly increases plasma Se levels in these patients; however, there are still not enough studies to clarify the effects of Se supplementation on the antioxidant and inflammatory markers, immune system and thyroid hormones. Further studies are needed to elucidate the effects of Se supplementation and to provide a recommendation for patients with CKD undergoing HD.Copyright © The Author(s), 2024. | - |
dc.publisher | Cambridge University Press | - |
dc.relation.ispartof | Nutrition Research Reviews | - |
dc.subject.mesh | chronic kidney failure | - |
dc.subject.mesh | dietary supplement | - |
dc.subject.mesh | hemodialysis | - |
dc.title | Selenium supplementation in chronic kidney disease patients undergoing haemodialysis: A systematic review of the effects on plasma selenium, antioxidant and inflammatory markers, immunological parameters and thyroid hormones. | - |
dc.type | Review | - |
dc.identifier.affiliation | Cardiology (MonashHeart) | - |
dc.type.studyortrial | Systematic review and/or meta-analysis | - |
dc.identifier.doi | http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1017/S0954422424000222 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.pubmedid | 39320843 [https://www.ncbi.nlm.nih.gov/pubmed/?term=39320843] | - |
dc.identifier.institution | (Trigueira, Mafra, Stockler-Pinto) Post-Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), RJ, Niteroi, Brazil | - |
dc.identifier.institution | (Trigueira, Stockler-Pinto) Post-Graduate Program in Pathology, Fluminense Federal University (UFF), RJ, Niteroi, Brazil | - |
dc.identifier.institution | (Leal) Pedro Ernesto University Hospital (HUPE), University of the State of Rio de Janeiro (UERJ), RJ, Rio de Janeiro, Brazil | - |
dc.identifier.institution | (Cardoso) Department of Nutrition, Dietetics and Food, Monash University, Melbourne, VIC, Australia | - |
dc.identifier.institution | (Cardoso) Victorian Heart Institute, Monash University, Clayton, VIC, Australia | - |
dc.identifier.institution | (Mafra) Post-Graduate Program in Medical Sciences, Fluminense Federal University (UFF), RJ, Niteroi, Brazil | - |
dc.identifier.institution | (Mafra) Post-Graduate Program in Biological Sciences-Physiology, Federal University of Rio de Janeiro (UFRJ), RJ, Rio de Janeiro, Brazil | - |
dc.identifier.institution | (Araujo) Sergio Arouca National School of Public Health-Oswaldo Cruz Foundation, Ministry of Health, RJ, Rio de Janeiro, Brazil | - |
dc.identifier.institution | (Stockler-Pinto) Post-Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), RJ, Niteroi, Brazil | - |
dc.identifier.affiliationmh | (Cardoso) Victorian Heart Institute, Monash University, Clayton, VIC, Australia | - |
item.openairetype | Review | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
Appears in Collections: | Articles |
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