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Title: | Community-wide active case finding for tuberculosis: time to use the evidence we have. | Authors: | Coleman M.;Lowbridge C.;du Cros P.;Marais B.J. | Monash Health Department(s): | Infectious Diseases and Clinical Microbiology | Institution: | (Coleman, Marais) Sydney Infectious Diseases Institute, University of Sydney, Sydney, NSW 2050, Australia (Coleman) Bordeaux Population Health, University of Bordeaux, Bordeaux 33076, France (Lowbridge) Division of Global & Tropical Health, Menzies School of Health Research, Charles Darwin University, Casuarina, NT 0810, Australia (du Cros) International Health, Burnet Institute, Melbourne, VIC 3004, Australia (du Cros) Department of Infectious Diseases, Monash Medical Centre, Clayton, VIC 3168, Australia (Marais) WHO Collaborating Centre for Tuberculosis, Sydney, NSW 2145, Australia |
Issue Date: | 30-Sep-2024 | Copyright year: | 2024 | Publisher: | Multidisciplinary Digital Publishing Institute (MDPI) | Place of publication: | Switzerland | Publication information: | Tropical Medicine and Infectious Disease. 9(9) (no pagination), 2024. Article Number: 214. Date of Publication: September 2024. | Journal: | Tropical Medicine and Infectious Disease | Abstract: | Tuberculosis, caused by the Mycobacterium tuberculosis (Mtb) bacteria, is one of the world's deadliest infectious diseases. Despite being the world's oldest pandemic, tuberculosis is very much a challenge of the modern era. In high-incidence settings, all people are at risk, irrespective of whether they have common vulnerabilities to the disease warranting the current WHO recommendations for community-wide tuberculosis active case finding in these settings. Despite good evidence of effectiveness in reducing tuberculosis transmission, uptake of this strategy has been lacking in the communities that would derive greatest benefit. We consider the various complexities in eliminating tuberculosis from the first principles of the disease, including diagnostic and other challenges that must be navigated under an elimination agenda. We make the case that community-wide tuberculosis active case finding is the best strategy currently available to drive elimination forward in high-incidence settings and that no time should be lost in its implementation. Recognizing that high-incidence communities vary in their epidemiology and spatiosocial characteristics, tuberculosis research and funding must now shift towards radically supporting local implementation and operational research in communities. This "preparing of the ground" for scaling up to community-wide intervention centers the local knowledge and local experience of community epidemiology to optimize implementation practices and accelerate reductions in community-level tuberculosis transmission.Copyright © 2024 by the authors. | DOI: | http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.3390/tropicalmed9090214 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/52604 | Type: | Review | Subjects: | communicable disease epidemiology Mycobacterium tuberculosis pandemic tuberculosis |
Type of Clinical Study or Trial: | Case series or case report |
Appears in Collections: | Articles |
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