Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/52786
Conference/Presentation Title: Novel vascular territory mapping algorithm as a predictive tool for identification of antegrade flow in MCA occlusion.
Authors: Valente M.;Parsons M.;Chen C. ;Visser M.;Ma H. ;Bivard A.
Monash Health Department(s): Neurology
Institution: (Valente, Ma) Department of Neurology, Monash Health, Clayton, VIC, Australia
(Valente, Visser, Bivard) Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia
(Parsons, Chen) University of New South Wales South Western Sydney Clinical School, Department of Neurology Liverpool Hospital, Ingham Institute of Applied Medical Research, Liverpool, Australia
(Chen) Faculty of Medicine, University of NSW, Sydney, NSW, Australia
Presentation/Conference Date: 13-Nov-2024
Copyright year: 2024
Publication information: Cerebrovascular Diseases. Conference: Asia Pacific Stroke Conference 2024 Combined Australian and New Zealand Stroke Organisation Transcending Borders. Adelaide, SA Australia. 53(Supplement 1) (pp 80), 2024. Date of Publication: 2024.
Journal: Cerebrovascular Diseases
Abstract: Background/Aims: Vascular territory mapping (VTM) software estimates which intracerebral vessel provides peak arterial flow to a brain voxel. We identify whether VTM software is a determinant of antegrade flow in patients with proximal MCA occlusion. Method(s): Consecutive patients with M1 occlusion were analysed from INSPIRE (International Stroke Perfusion Imaging Registry). Authors reviewed dynamic 4D CTA for the presence an acute M1 thrombus and antegrade flow. VTM software assigned regions of the brain to an estimated feeding vessel (ACA, MCA, PCA). A binomial logistic regression was performed to determine the effects of VTM, ischaemic core (CBF<30) and perfusion lesion (DT>3) on the likelihood that patients had the presence of any antegrade flow in the MCA territory. A secondary analysis was performed to assess the relationship between imaging variables and 3-month MRS outcome. Result(s): The final dataset included 130 patients with M1 occlusion, and 18 patients were identified with antegrade flow on 4D DSA. Patients with antegrade flow had significantly larger VTM MCA volumes, 101ml (72-180), compared to those with complete occlusion, 41ml (21-71). VTM MCA volume significantly predicted antegrade flow, with increase in odds per unit volume (1ml) of 1.024 (95% CI, 1.013 to 1.036), p = <0.001. Ischemic core and the perfusion lesion did not significantly improve model prediction of antegrade flow. Conclusion(s): VTM software was more effective than traditional perfusion parameters in the detection of antegrade flow.
Conference Name: Asia Pacific Stroke Conference 2024 Combined Australian and New Zealand Stroke Organisation Transcending Borders
Conference Start Date: 2024-09-25
Conference End Date: 2024-09-28
Conference Location: Adelaide, SA, Australia
DOI: http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1159/000541320
URI: https://repository.monashhealth.org/monashhealthjspui/handle/1/52786
Type: Conference Abstract
Subjects: cerebrovascular accident
digital subtraction angiography
scintigraphy
vascularization
Type of Clinical Study or Trial: Observational study (cohort, case-control, cross sectional, or survey)
Appears in Collections:Conferences

Show full item record

Page view(s)

38
checked on Mar 13, 2025

Google ScholarTM

Check


Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.