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Conference/Presentation Title: | Novel vascular territory mapping algorithm as a predictive tool for identification of antegrade flow in MCA occlusion. | Authors: | Valente M.;Parsons M.;Chen C. ;Visser M.;Ma H. ;Bivard A. | Monash Health Department(s): | Neurology | Institution: | (Valente, Ma) Department of Neurology, Monash Health, Clayton, VIC, Australia (Valente, Visser, Bivard) Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (Parsons, Chen) University of New South Wales South Western Sydney Clinical School, Department of Neurology Liverpool Hospital, Ingham Institute of Applied Medical Research, Liverpool, Australia (Chen) Faculty of Medicine, University of NSW, Sydney, NSW, Australia |
Presentation/Conference Date: | 13-Nov-2024 | Copyright year: | 2024 | Publication information: | Cerebrovascular Diseases. Conference: Asia Pacific Stroke Conference 2024 Combined Australian and New Zealand Stroke Organisation Transcending Borders. Adelaide, SA Australia. 53(Supplement 1) (pp 80), 2024. Date of Publication: 2024. | Journal: | Cerebrovascular Diseases | Abstract: | Background/Aims: Vascular territory mapping (VTM) software estimates which intracerebral vessel provides peak arterial flow to a brain voxel. We identify whether VTM software is a determinant of antegrade flow in patients with proximal MCA occlusion. Method(s): Consecutive patients with M1 occlusion were analysed from INSPIRE (International Stroke Perfusion Imaging Registry). Authors reviewed dynamic 4D CTA for the presence an acute M1 thrombus and antegrade flow. VTM software assigned regions of the brain to an estimated feeding vessel (ACA, MCA, PCA). A binomial logistic regression was performed to determine the effects of VTM, ischaemic core (CBF<30) and perfusion lesion (DT>3) on the likelihood that patients had the presence of any antegrade flow in the MCA territory. A secondary analysis was performed to assess the relationship between imaging variables and 3-month MRS outcome. Result(s): The final dataset included 130 patients with M1 occlusion, and 18 patients were identified with antegrade flow on 4D DSA. Patients with antegrade flow had significantly larger VTM MCA volumes, 101ml (72-180), compared to those with complete occlusion, 41ml (21-71). VTM MCA volume significantly predicted antegrade flow, with increase in odds per unit volume (1ml) of 1.024 (95% CI, 1.013 to 1.036), p = <0.001. Ischemic core and the perfusion lesion did not significantly improve model prediction of antegrade flow. Conclusion(s): VTM software was more effective than traditional perfusion parameters in the detection of antegrade flow. | Conference Name: | Asia Pacific Stroke Conference 2024 Combined Australian and New Zealand Stroke Organisation Transcending Borders | Conference Start Date: | 2024-09-25 | Conference End Date: | 2024-09-28 | Conference Location: | Adelaide, SA, Australia | DOI: | http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1159/000541320 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/52786 | Type: | Conference Abstract | Subjects: | cerebrovascular accident digital subtraction angiography scintigraphy vascularization |
Type of Clinical Study or Trial: | Observational study (cohort, case-control, cross sectional, or survey) |
Appears in Collections: | Conferences |
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