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Title: | Impact of obstructive sleep apnoea on diabetes and cardiovascular disease. | Authors: | Naughton M.T.;Hamilton G.S. | Institution: | (Hamilton) Monash Medical Centre, Melbourne, VIC, Australia. | Issue Date: | 12-Jan-2014 | Copyright year: | 2013 | Place of publication: | Australia | Publication information: | The Medical journal of Australia. 199 (8) (pp S27-30), 2013. Date of Publication: 21 Oct 2013. | Abstract: | Obstructive sleep apnoea (OSA) is a potential cause of systemic hypertension in young and middle-aged people, and treatment helps reduce blood pressure in some patients. Severe OSA (apnoea-hypopnoea index [AHI] > 30/h) is strongly associated with increased mortality, stroke and cardiovascular disease in middle-aged populations. The cardiovascular risk from moderate OSA (AHI, 15-30/h) is uncertain, particularly if the oxygen desaturation index is low, although the data suggest an increased risk for stroke (particularly in men). There is no evidence of increased cardiovascular risk from mild OSA (AHI < 15/h). In the elderly, the cardiovascular risks of OSA are uncertain, although there is a likelihood of increased risk of stroke. Current, ongoing randomised controlled trials will inform whether OSA is a reversible cardiovascular risk factor within the next 5 years. Patients with cardiovascular disease, stroke, diabetes, obesity or poorly controlled hypertension are at high risk of OSA and should be questioned for symptoms of OSA, which, if present, may warrant further investigation and treatment. Weight loss has an unpredictable effect on OSA severity, but is independently beneficial for symptoms and metabolic health in OSA patients and is recommended for all overweight and obese OSA patients. | Link to associated publication: | Click here for full text options | PubMed URL: | 24138362 [http://www.ncbi.nlm.nih.gov/pubmed/?term=24138362] | ISSN: | 1326-5377 (electronic) | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/28087 | Type: | Article | Subjects: | middle aged adult age aged article Australia *cardiovascular disease/co [Complication] *cardiovascular disease/di [Diagnosis] cause of death human lifestyle mortality *non insulin dependent diabetes mellitus/co [Complication] *non insulin dependent diabetes mellitus/di [Diagnosis] obesity/co [Complication] patient compliance risk factor *sleep disordered breathing/co [Complication] *sleep disordered breathing/di [Diagnosis] *sleep disordered breathing/et [Etiology] weight reduction human lifestyle middle aged mortality *non insulin dependent diabetes mellitus / *complication / *diagnosis obesity / complication patient compliance risk factor *sleep disordered breathing / *complication / *diagnosis / *etiology weight reduction Australia adult cause of death aged age *cardiovascular disease / *complication / *diagnosis article |
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