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https://repository.monashhealth.org/monashhealthjspui/handle/1/28360| Title: | The Ductus Arteriosus: A Refined Approach!. | Authors: | Sehgal A. ;McNamara P.J. | Institution: | (Sehgal) Monash Newborn, Monash Medical Centre, Clayton, VIC, Australia (Sehgal) Department of Pediatrics, Monash University, Clayton, VIC, Australia (McNamara) Division of Neonatology, The Hospital for Sick Children, Toronto, ON, Canada (McNamara) Physiology and Experimental Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada (McNamara) Department of Pediatrics, University of Toronto, Toronto, ON, Canada | Issue Date: | 26-Mar-2012 | Copyright year: | 2012 | Publisher: | W.B. Saunders (Independence Square West, Philadelphia PA 19106-3399, United States) | Place of publication: | United States | Publication information: | Seminars in Perinatology. 36 (2) (pp 105-113), 2012. Date of Publication: April 2012. | Abstract: | Although ongoing patency of the ductus arteriosus is common in small extremely preterm infants, consensus is lacking regarding its clinical significance and treatment strategies. Literature regarding likelihood of spontaneous closure, impact on neonatal morbidity and long-term outcomes, and adverse effects of intervention has led to uncertainty as to the best course of action. Enhancing the determination of hemodynamic significance and refining patient selection for therapeutic intervention will streamline the decision-making process. Targeted neonatal echocardiography performed by the clinician has gained popularity worldwide, and preliminary data show that it has the potential to optimize patient outcomes. We review the arguments for and against medical and surgical therapy, explore how targeted neonatal echocardiography used in conjunction with biomarkers may refine the treatment approach, and consider future directions in the field. © 2012 Elsevier Inc. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1053/j.semperi.2011.09.020 | PubMed URL: | 22414881 [http://www.ncbi.nlm.nih.gov/pubmed/?term=22414881] | ISSN: | 0146-0005 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/28360 | Type: | Review | Subjects: | necrotizing enterocolitis/si [Side Effect] newborn morbidity nonhuman *patent ductus arteriosus/di [Diagnosis] *patent ductus arteriosus/su [Surgery] patent ductus arteriosus/dt [Drug Therapy] postoperative complication/co [Complication] prematurity priority journal randomized controlled trial (topic) review risk factor side effect/si [Side Effect] indometacin/ae [Adverse Drug Reaction] indometacin/ct [Clinical Trial] indometacin/dt [Drug Therapy] nonsteroid antiinflammatory agent/ct [Clinical Trial] nonsteroid antiinflammatory agent/dt [Drug Therapy] *patent ductus arteriosus/dt [Drug Therapy] artery ligation coronary artery blood flow disease classification disease marker Doppler echography ductus arteriosus echocardiography human intestine perforation/et [Etiology] intestine perforation/si [Side Effect] kidney disease/si [Side Effect] necrotizing enterocolitis/dt [Drug Therapy] necrotizing enterocolitis/et [Etiology] kidney disease / side effect necrotizing enterocolitis / drug therapy / etiology / side effect newborn morbidity nonhuman *patent ductus arteriosus / *diagnosis / *drug therapy / *surgery patent ductus arteriosus / drug therapy postoperative complication / complication prematurity priority journal artery ligation review risk factor side effect / side effect randomized controlled trial (topic) coronary artery blood flow disease classification disease marker Doppler echography ductus arteriosus echocardiography human intestine perforation / etiology / side effect |
Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
| Appears in Collections: | Articles |
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