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Title: | Tertiary lymphoid tissue in kidneys: understanding local immunity and inflammation. | Authors: | Kitching A.R. ;Robson K.J. | Monash Health Department(s): | Centre for Inflammatory Diseases at Monash Health Paediatric - Nephrology Nephrology |
Institution: | (Robson, Kitching) Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia (Kitching) Department of Nephrology, Monash Health, Clayton, Victoria, Australia (Kitching) Department of Pediatric Nephrology, Monash Health, Clayton, Victoria, Australia | Issue Date: | 20-Jul-2020 | Copyright year: | 2020 | Publisher: | Elsevier B.V. | Place of publication: | Netherlands | Publication information: | Kidney International. 98 (2) (pp 280-283), 2020. Date of Publication: August 2020. | Journal: | Kidney International | Abstract: | Tertiary lymphoid tissues are peripheral foci of immune activity that develop in kidneys and other peripheral organs in the context of chronic inflammation. In this issue of Kidney International, Sato and colleagues present a detailed characterization of tertiary lymphoid tissues in mouse and human kidneys in the context of acute kidney injury, chronic pyelonephritis, aging, and chronic kidney disease, showing the importance of nontraditional roles of B cells in the inflamed kidney microenvironment.Copyright © 2020 International Society of Nephrology | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1016/j.kint.2020.04.026 | PubMed URL: | 32709287 [http://www.ncbi.nlm.nih.gov/pubmed/?term=32709287] | ISSN: | 0085-2538 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/28874 | Type: | Note | Subjects: | glomerulonephritis graft rejection Helicobacter pylori hepatitis C immunoglobulin A nephropathy immunohistochemistry infection Influenza virus kidney kidney allograft rejection kidney transplantation lupus erythematosus nephritis lymphangiogenesis lymphocyte proliferation lymphoid cell memory cell mononuclear cell multiple sclerosis Mycobacterium tuberculosis nephrectomy rheumatoid arthritis Sjoegren syndrome T lymphocyte activation tertiary lymphoid structure tumor growth upregulation CXCL13 chemokine Ki 67 antigen rituximab secondary lymphoid tissue chemokine acute kidney failure aging ANCA associated vasculitis autoimmune disease autoimmunity B lymphocyte cancer research cell infiltration cell survival chronic kidney failure chronic pyelonephritis cytokine production cytokine release fibroblast |
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