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Title: | Fractional Flow Reserve following Percutaneous Coronary Intervention. | Authors: | Ko B. ;Michail M.;Ihdayhid A.R.;Poon E.;Nicholls S.J.;Brown A.J.;Thakur U.;Khav N.;Comella A. | Monash Health Department(s): | Cardiology (MonashHeart) | Institution: | (Thakur, Khav, Comella, Michail, Ihdayhid, Nicholls, Ko, Brown) Monash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, Australia (Michail) Institute of Cardiovascular Science, University College London, London, United Kingdom (Poon) Department of Mechanical Engineering, University of Melbourne, Parkville, Australia | Issue Date: | 1-Jul-2020 | Copyright year: | 2020 | Publisher: | Hindawi Limited (410 Park Avenue, 15th Floor, 287 pmb, New York NY 10022, United States) | Place of publication: | United States | Publication information: | Journal of Interventional Cardiology. 2020 (no pagination), 2020. Article Number: 7467943. Date of Publication: 2020. | Journal: | Journal of Interventional Cardiology | Abstract: | Fractional flow reserve (FFR) is routinely used to determine lesion severity prior to percutaneous coronary intervention (PCI). However, there is an increasing recognition that FFR may also be useful following PCI to identify mechanisms leading to restenosis and the need for repeat revascularization. Post-PCI FFR is associated with the presence and severity of stent under-expansion and may help identify peri-stent-related complications. FFR pullback may also unmask other functionally significant lesions within the target vessel that were not appreciable on angiography. Recent studies have confirmed the prognostic utility of performing routine post-PCI FFR and suggest possible interventional targets that would improve stent durability. In this review, we detail the theoretical basis underlying post-PCI FFR, provide practical tips to facilitate measurement, and discuss the growing evidence supporting its use.Copyright © 2020 Udit Thakur et al. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1155/2020/7467943 | PubMed URL: | 32565755 [http://www.ncbi.nlm.nih.gov/pubmed/?term=32565755] | ISSN: | 0896-4327 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/29168 | Type: | Review | Subjects: | angiography blood vessel compliance clinical outcome coronary artery coronary artery disease/th [Therapy] coronary bifurcation lesion/th [Therapy] coronary stenting *fractional flow reserve human in-stent restenosis/co [Complication] intravascular ultrasound major adverse cardiac event microangiopathy/co [Complication] *percutaneous coronary intervention priority journal review risk assessment risk factor shear stress ST segment elevation myocardial infarction/th [Therapy] stable angina pectoris/th [Therapy] stent thrombosis/co [Complication] bare metal stent coronary stent/am [Adverse Device Effect] drug eluting stent endothelial shear stress optical coherence tomography acute coronary syndrome/th [Therapy] angiography blood vessel compliance coronary artery coronary artery disease coronary bifurcation lesion coronary stenting fractional flow reserve in-stent restenosis/co intravascular ultrasound major adverse cardiac event microangiopathy/co percutaneous coronary intervention shear stress ST segment elevation myocardial infarction stable angina pectoris stent thrombosis/co bare metal stent coronary stent/am [Adverse Device Effect] drug eluting stent endothelial shear stress optical coherence tomography acute coronary syndrome intravascular ultrasound major adverse cardiac event microangiopathy / complication optical coherence tomography *percutaneous coronary intervention priority journal Review risk assessment risk factor shear stress ST segment elevation myocardial infarction / therapy stable angina pectoris / therapy stent thrombosis / complication coronary artery disease / therapy coronary artery clinical outcome blood vessel compliance acute coronary syndrome / therapy coronary stenting *fractional flow reserve human in-stent restenosis / complication angiography coronary bifurcation lesion / therapy |
Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
Appears in Collections: | Articles |
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