Please use this identifier to cite or link to this item:
https://repository.monashhealth.org/monashhealthjspui/handle/1/29784
Title: | Hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome in a 26-year-old woman with cystic fibrosis: A case report. | Authors: | Dabscheck E.;Reid D.;Geake J. | Institution: | (Geake) Department of Respiratory and Sleep Medicine, Monash Medical Centre, 246 Clayton Road, Clayton 3168, Australia (Geake, Dabscheck) Department of Respiratory Medicine, Hobart, TAS 7001, Australia (Dabscheck) Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Commercial Road, Prahan, Melbourne 3181, Australia (Reid) Adult Cystic Fibrosis Centre, Prince Charles Hospital, Rode Road, Chermside, QLD 4032, Australia (Reid) Tasmanian Adult Cystic Fibrosis Unit, Hobart, TAS 7001, Australia | Issue Date: | 5-Dec-2012 | Copyright year: | 2012 | Publisher: | BioMed Central Ltd. (Floor 6, 236 Gray's Inn Road, London WC1X 8HB, United Kingdom) | Place of publication: | United Kingdom | Publication information: | Journal of Medical Case Reports. 6 (no pagination), 2012. Article Number: 134. Date of Publication: 2012. | Abstract: | Introduction: The microangiopathic hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome is a rare and potentially fatal complication of pregnancy. Here, to the best of our knowledge, we describe only the second reported case of this syndrome in a woman with cystic fibrosis. Case presentation: This report describes the case of a 26-year-old woman of Caucasian ethnicity with mild cystic fibrosis bronchiectasis who ultimately manifested the triad of microangiopathic hemolysis, elevated liver enzymes, and low platelet count in the third trimester of pregnancy. Her baby was delivered successfully after a semi-elective caesarean section. Conclusion(s): Pregnancies in patients with cystic fibrosis are associated with an increased rate of complications. This case is of importance as it describes only for the second time the successful delivery of a baby in a women with cystic fibrosis, in a pregnancy also threatened by the microangiopathic hemolysis, elevated liver enzymes, and low platelet syndrome. This case will be of special interest to obstetricians, pediatricians, and medical, nursing and allied health staff involved in the delivery of cystic fibrosis care. © 2012 Geake et al.; licensee BioMed Central Ltd. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1186/1752-1947-6-134 | ISSN: | 1752-1947 (electronic) | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/29784 | Type: | Article | Subjects: | case report Caucasian cesarean section corticosteroid therapy creatinine urine level *cystic fibrosis diabetes mellitus/dt [Drug Therapy] disease exacerbation elective surgery female fetus lung maturation follow up forced expiratory volume gestational age glycemic control *HELLP syndrome/dt [Drug Therapy] HELLP syndrome/dt [Drug Therapy] hemoglobin blood level high risk pregnancy human insulin treatment lactate dehydrogenase blood level lung disease lung function membrane rupture nausea/si [Side Effect] outpatient care pancreas insufficiency preeclampsia priority journal protein urine level Pseudomonas infection spinal anesthesia systolic blood pressure third trimester pregnancy aztreonam/dt [Drug Therapy] aztreonam/iv [Intravenous Drug Administration] betamethasone/cb [Drug Combination] betamethasone/dt [Drug Therapy] betamethasone/im [Intramuscular Drug Administration] ciprofloxacin/ae [Adverse Drug Reaction] ciprofloxacin/po [Oral Drug Administration] creatinine/ec [Endogenous Compound] hemoglobin/ec [Endogenous Compound] hemoglobin A1c/ec [Endogenous Compound] insulin/dt [Drug Therapy] lactate dehydrogenase/ec [Endogenous Compound] metoclopramide/po [Oral Drug Administration] drug tolerability thrombocyte count treatment duration unplanned pregnancy urinalysis vaginal delivery alanine aminotransferase/ec [Endogenous Compound] albumin/ec [Endogenous Compound] aztreonam/cb [Drug Combination] adult alanine aminotransferase blood level Apgar score article blood pressure body mass bronchiectasis diabetes mellitus / drug therapy disease exacerbation drug tolerability elective surgery female fetus lung maturation follow up forced expiratory volume gestational age glycemic control *HELLP syndrome / *drug therapy HELLP syndrome / drug therapy hemoglobin blood level high risk pregnancy human insulin treatment lactate dehydrogenase blood level lung disease lung function membrane rupture nausea / side effect outpatient care pancreas insufficiency preeclampsia priority journal protein urine level Pseudomonas infection spinal anesthesia systolic blood pressure body mass thrombocyte count treatment duration unplanned pregnancy urinalysis vaginal delivery blood pressure article Apgar score alanine aminotransferase blood level adult third trimester pregnancy bronchiectasis case report Caucasian cesarean section corticosteroid therapy creatinine urine level *cystic fibrosis |
Type of Clinical Study or Trial: | Case series or case report |
Appears in Collections: | Articles |
Show full item record
Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.