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https://repository.monashhealth.org/monashhealthjspui/handle/1/30256| Title: | Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding. | Authors: | Giles M. ;Sasadeusz J.;Visvanathan K. | Institution: | (Giles, Sasadeusz) Infectious Diseases Unit, Alfred Hospital, Melbourne, VIC, Australia (Giles, Visvanathan) Department of Infectious Diseases, Monash Medical Centre, Melbourne, VIC, Australia (Giles) Department of Microbiology and Infectious Diseases, Royal Women's Hospital, Melbourne, VIC, Australia (Giles, Visvanathan) Department of Medicine, Monash University, Melbourne, VIC, Australia (Giles, Sasadeusz) Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, VIC, Australia | Issue Date: | 8-Oct-2012 | Copyright year: | 2011 | Publisher: | International Medical Press Ltd (2-4 Idol Lane, London EC3R 5DD, United Kingdom) | Place of publication: | United Kingdom | Publication information: | Antiviral Therapy. 16 (5) (pp 621-628), 2011. Date of Publication: 2011. | Abstract: | It is estimated there are 350-400 million people worldwide chronically infected with HBV. Many of these are women and of reproductive age. As such, they may face therapeutic decisions regarding antiviral therapy and the implication this may have on future or current pregnancies. This article reviews the data of all antivirals licensed for use against hepatitis B infection regarding teratogenicity, carcinogenicity, clinical experience during pregnancy, placental transfer and excretion in breast milk. ©2011 International Medical Press. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.3851/IMP1813 | PubMed URL: | 21817183 [http://www.ncbi.nlm.nih.gov/pubmed/?term=21817183] | ISSN: | 1359-6535 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/30256 | Type: | Review | Subjects: | placental transfer prenatal drug exposure priority journal reproductive toxicity review single drug dose teratogenicity virus transmission adefovir/cm [Drug Comparison] adefovir dipivoxil/dt [Drug Therapy] adefovir dipivoxil/to [Drug Toxicity] adefovir dipivoxil/iv [Intravenous Drug Administration] adefovir dipivoxil/pd [Pharmacology] alpha interferon/cr [Drug Concentration] alpha interferon/dt [Drug Therapy] alpha interferon/to [Drug Toxicity] alpha interferon/im [Intramuscular Drug Administration] alpha interferon/iv [Intravenous Drug Administration] alpha interferon/pk [Pharmacokinetics] alpha interferon/pd [Pharmacology] entecavir/cm [Drug Comparison] entecavir/dt [Drug Therapy] entecavir/to [Drug Toxicity] entecavir/iv [Intravenous Drug Administration] entecavir/pk [Pharmacokinetics] entecavir/pd [Pharmacology] lamivudine/cm [Drug Comparison] lamivudine/cr [Drug Concentration] lamivudine/dt [Drug Therapy] lamivudine/to [Drug Toxicity] lamivudine/po [Oral Drug Administration] lamivudine/pk [Pharmacokinetics] lamivudine/pd [Pharmacology] placebo telbivudine/cm [Drug Comparison] telbivudine/dt [Drug Therapy] telbivudine/to [Drug Toxicity] telbivudine/pk [Pharmacokinetics] telbivudine/pd [Pharmacology] tenofovir/cm [Drug Comparison] tenofovir/dt [Drug Therapy] tenofovir/to [Drug Toxicity] tenofovir/pk [Pharmacokinetics] tenofovir/pd [Pharmacology] tenofovir/sc [Subcutaneous Drug Administration] *antiviral therapy breast feeding drug blood level drug carcinogenicity drug efficacy drug excretion *drug milk level fetotoxicity *hepatitis B/dt [Drug Therapy] hepatitis B/dt [Drug Therapy] human intrauterine infection/dt [Drug Therapy] *intrauterine infection/dt [Drug Therapy] maternal blood nonhuman nonhuman placental transfer prenatal drug exposure priority journal reproductive toxicity review single drug dose teratogenicity virus transmission drug excretion drug carcinogenicity drug blood level breast feeding *antiviral therapy drug efficacy *drug milk level fetotoxicity *hepatitis B / *drug therapy hepatitis B / drug therapy human intrauterine infection / drug therapy *intrauterine infection / *drug therapy maternal blood |
Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
| Appears in Collections: | Articles |
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