The antiphospholipid antibody syndrome.

Abstract

BACKGROUND: Recurrent miscarriages cause enormous distress and despair for sufferers. In a small number of patients this condition forms part of the antiphospholipid antibody syndrome. The anticardiolipin antibodies became quantifiable in 1983, which has meant that those suffering with this condition could be identified. OBJECTIVE(S): This article reviews the current understanding of this condition and offers an approach for managing patients with various components of this syndrome. DISCUSSION: The decision to screen for these antibodies is sometimes difficult as they can be presented in the normal population. However, by identifying the patient suffering with this condition, treatment can offered which may prevent a further miscarriage or a pregnant patient suffering a thromboembolic episode.