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https://repository.monashhealth.org/monashhealthjspui/handle/1/34903| Title: | Age, sex, and setting in the etiology of stroke study (ASSESS): Study design and protocol. | Authors: | Swartz R.H.;Amiri A.;Kapral M.K.;Yassi N.;Bahit C.;Kaul S.;Alladi S.;Nilanont Y.;Coppola M.;Nucera A.;Silver B.;Werring D.;Simister R.;Owolabi M.O.;Hachinski V.;Ovbiagele B.;Azarpazhooh M.R.;Mandzia J.L.;Thrift A.G. ;Sposato L.A.;Morovatdar N. | Institution: | (Azarpazhooh, Amiri) Department of Neurology, Ghaem hospital, Mashhad University of Medical Sciences, Mashhad, Iran, Islamic Republic of (Azarpazhooh, Mandzia, Sposato, Hachinski) Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Center, Western University, ON, Canada (Azarpazhooh, Sposato, Hachinski) Department of Epidemiology and Biostatistics, Western University, ON, Canada (Thrift) Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia (Sposato) Department of Anatomy and Cell Biology, Western University, ON, Canada (Sposato) Stroke, Dementia, and Heart Disease Lab, Western University, ON, Canada (Morovatdar) Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, Islamic Republic of (Kapral) Department of Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada (Yassi) Departments of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (Bahit) Cardiology Department, INECO Neurociencias Orono, Rosario, Santa Fe, Argentina (Kaul) Department of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, India (Alladi) National Institute of Mental Health and Neurosciences, Bengaluru, India (Nilanont) Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand (Coppola) Hospital Ramon, Santamarin, Tandil, Argentina (Nucera) Department of Neurology, Saint Andrea Hospital, Stroke Unit, La Spezia, Italy (Silver) Department of Neurology, The University of Massachusetts Medical School and UMass Memorial Medical Center, Worcester, MA, United States (Werring) Stroke Research Centre, UCL Institute of Neurology, London, United Kingdom (Simister) University College London Hospitals NHS Foundation Trust, London, United Kingdom (Swartz) Department of Medicine, Division of Neurology, Sunnybrook HSC, University of Toronto, Toronto, Canada (Owolabi) Center for Genomic and Precision Medicine, University of Ibadan, Nigeria (Ovbiagele) Department of Neurology, University of California, San Francisco, United States | Issue Date: | 8-Mar-2019 | Copyright year: | 2019 | Publisher: | Elsevier B.V. | Place of publication: | Netherlands | Publication information: | Journal of the Neurological Sciences. 399 (pp 209-213), 2019. Date of Publication: 15 April 2019. | Journal: | Journal of the Neurological Sciences | Abstract: | Rationale: Stroke etiology and risk factors vary by age, sex, setting (hospital or community-based) and by region. Identifying these differences would improve our understanding of stroke etiology, diagnosis, and treatment. Aim(s): The Age, Sex and Setting in the Etiology of Stroke Study (ASSESS) is a multicenter cohort study to assess differences in stroke etiology. Methods and design: Data from all centers will be categorized according to age, sex, setting, stroke subtypes. Centers with extensive hospital- or community-based data regarding stroke from Argentina, Australia, Canada, India, Iran, Italy, Ghana, Nigeria, Thailand, the United Kingdom and the United States have agreed to participate so far. Study outcomes: The primary outcome includes differences in stroke etiology in study centers. The secondary outcomes include stroke incidence, risk factors, preventive strategies, and short- and long-term outcomes. Conclusion(s): ASSESS will enable comparisons of data from different regions to determine the age and sex distribution of the most common causes of stroke in each setting. This will help clinicians to tailor the assessment and treatment of stroke patients on the basis of their specific local characteristics. It will also empower stroke epidemiologists to design preventive measures by targeting the specific characteristics of each population.Copyright © 2019 | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1016/j.jns.2019.02.024 | PubMed URL: | 30851659 [http://www.ncbi.nlm.nih.gov/pubmed/?term=30851659] | ISSN: | 0022-510X | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/34903 | Type: | Article | Type of Clinical Study or Trial: | Observational study (cohort, case-control, cross sectional or survey) |
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