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https://repository.monashhealth.org/monashhealthjspui/handle/1/35386| Title: | Atypical severe progressive perioral ulceration due to herpes simplex virus on the background of undiagnosed HIV/AIDS. | Authors: | Poon F.;Chong A.H.;Kelmann A.;Milne O.J.;Howard M.D. | Monash Health Department(s): | Dermatology Pathology |
Institution: | (Howard) Victorian Melanoma Service, Alfred Hospital, Melbourne, VIC, Australia (Poon, Milne) Department of Dermatology, Monash Health, Clayton, VIC, Australia (Kelmann) Department of Pathology, Monash Health, Clayton, VIC, Australia (Chong) Skin & Cancer Foundation Inc., Melbourne, VIC, Australia (Chong) Department of Medicine, St Vincent's Hospital, University of Melbourne, Melbourne, VIC, Australia | Issue Date: | 29-Feb-2020 | Copyright year: | 2020 | Publisher: | Blackwell Publishing | Place of publication: | Australia | Publication information: | Australasian Journal of Dermatology. 61 (1) (pp e79-e81), 2020. Date of Publication: 01 Feb 2020. | Journal: | Australasian Journal of Dermatology | Abstract: | Perioral ulcerative plaques have a broad list of differential diagnoses. We describe an unusual presentation of chronic progressive perioral ulceration due to herpes simplex type (HSV)-1 on a background of undiagnosed human immunodeficiency virus infection with acquired immunodeficiency syndrome. Whilst chronic mucocutaneous HSV is an AIDS-defining condition with both HSV-1 and HSV-2 implicated, typical reported cases describe vesicular eruptions rather than perioral ulcerative plaques. This case highlights that common infections may present atypically in immunocompromised individuals and may be a clue to underlying systemic illness.Copyright © 2019 The Australasian College of Dermatologists | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/ajd.13111 | PubMed URL: | 31266092 [http://www.ncbi.nlm.nih.gov/pubmed/?term=31266092] | ISSN: | 0004-8380 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/35386 | Type: | Article | Subjects: | *herpes simplex/dt [Drug Therapy] histopathology hospital acquired pneumonia/dt [Drug Therapy] hospital acquired pneumonia/pc [Prevention] human *Human immunodeficiency virus infection/di [Diagnosis] *Human immunodeficiency virus infection/dt [Drug Therapy] human tissue immunohistochemistry male medical history *mouth ulcer/di [Diagnosis] oral biopsy pneumocystosis/dt [Drug Therapy] pneumocystosis/pc [Prevention] refugee sigmoidoscopy single drug dose Sri Lanka Sri Lankan travel treatment duration cotrimoxazole/dt [Drug Therapy] dolutegravir/cb [Drug Combination] dolutegravir/dt [Drug Therapy] emtricitabine plus tenofovir alafenamide/dt [Drug Therapy] famciclovir/cb [Drug Combination] famciclovir/dt [Drug Therapy] moxifloxacin/dt [Drug Therapy] penicillin G/dt [Drug Therapy] penicillin G/im [Intramuscular Drug Administration] thiamine/dt [Drug Therapy] valganciclovir/dt [Drug Therapy] differential diagnosis *acquired immune deficiency syndrome/di [Diagnosis] adult anus fissure anus fistula article body weight loss case report clinical article cytomegalovirus infection/dt [Drug Therapy] cytomegalovirus infection/pc [Prevention] debridement *disease course *disease severity drug substitution family counseling fever/co [Complication] *herpes simplex/di [Diagnosis] herpes simplex histopathology hospital acquired pneumonia immunodeficiency virus infection immunohistochemistry medical history mouth ulcer oral biopsy pneumocystosis refugee sigmoidoscopy single drug dose Sri Lanka Sri Lankan travel cotrimoxazole dolutegravir emtricitabine plus tenofovir alafenamide famciclovir moxifloxacin penicillin G penicillin G/im [Intramuscular Drug Administration] thiamine valganciclovir differential acquired immune deficiency syndrome anus fissure anus fistula body weight loss cytomegalovirus infection debridement disease course drug substitution family counseling fever/co herpes simplex *disease course *disease severity drug substitution family counseling fever / complication *herpes simplex / *diagnosis / *drug therapy histopathology hospital acquired pneumonia / drug therapy / prevention human *Human immunodeficiency virus infection / *diagnosis / *drug therapy human tissue immunohistochemistry male medical history *mouth ulcer / *diagnosis oral biopsy pneumocystosis / drug therapy / prevention refugee sigmoidoscopy single drug dose Sri Lanka adult travel treatment duration *acquired immune deficiency syndrome / *diagnosis Sri Lankan anus fissure anus fistula Article body weight loss case report clinical article cytomegalovirus infection / drug therapy / prevention debridement differential diagnosis |
Type of Clinical Study or Trial: | Case series or case report |
| Appears in Collections: | Articles |
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