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Title: | Urinary tract infections in Australian aged care homes: Antibiotic prescribing practices and concordance to national guidelines. | Authors: | Buising K.;Dowson L.;Bennett N.;Marshall C.;Kong D.C.M.;Stuart R.L. ;Friedman N.D. | Monash Health Department(s): | Infectious Diseases and Clinical Microbiology Infection Prevention and Epidemiology |
Institution: | (Dowson, Bennett, Buising, Marshall, Friedman, Stuart, Kong) National Centre for Antimicrobial Stewardship at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia (Dowson, Kong) Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia (Bennett) Victorian Healthcare Associated Infection Surveillance System Coordinating Centre at, The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia (Bennett) Department of Nursing, Melbourne School of Health Sciences, The University of Melbourne, Carlton, Victoria, Australia (Buising, Marshall) Victorian Infectious Diseases Service at, The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia (Buising, Marshall) Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia (Marshall) Infection Prevention and Surveillance Service, The Royal Melbourne Hospital, Parkville, Victoria, Australia (Friedman) School of Medicine, Deakin University, Geelong, Victoria, Australia (Friedman) Department of General Medicine and Department of Infectious Diseases, Barwon Health, Geelong, Victoria, Australia (Stuart) Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia (Stuart) Monash Infectious Diseases and Infection Control and Epidemiology, Monash Health, Clayton, Victoria, Australia (Kong) Pharmacy Department, Ballarat Health Services, Ballarat, Victoria, Australia | Issue Date: | 4-Mar-2020 | Copyright year: | 2020 | Publisher: | Mosby Inc. (E-mail: customerservice@mosby.com) | Place of publication: | United States | Publication information: | American Journal of Infection Control. 48 (3) (pp 261-266), 2020. Date of Publication: March 2020. | Journal: | American Journal of Infection Control | Abstract: | Background: Since 2015 the Aged Care National Antimicrobial Prescribing Survey has collected and reported data on antibiotic use in Australian aged care homes (ACHs) as part of the Australian Commission on Safety and Quality in Health Care's Antimicrobial Use and Resistance in Australia project. The objective of this study was to analyze this data source with regards to prescribing for urinary tract infections (UTIs) to improve the use of antibiotics. Method(s): This cross-sectional study analyzed the 2016 and 2017 survey data. Antibiotic prescribing for urinary tract indications was compared with national guideline recommendations. Result(s): A total of 662 antibiotic prescriptions from 247 ACHs were analyzed. For all prophylactic antibiotics for UTI, 51.8% were prescribed for longer than 6 months, contrary to the guideline recommendation. Most antibiotics prescribed for treatment (71.6%) were for cystitis. Cefalexin was most frequently selected for treatment of cystitis, with 10.4% of these prescriptions being concordant with the recommendations. Prescribing additional daily doses of cefalexin occurred in 63.2% of prescriptions. Conclusion(s): Antimicrobial stewardship activities targeting UTI prophylaxis for durations longer than 6 months, and excessive daily doses of cefalexin to treat cystitis could yield significant reductions in unnecessary antibiotic consumption among Australian residents of ACHs.Copyright © 2019 | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1016/j.ajic.2019.08.034 | PubMed URL: | 31677924 [http://www.ncbi.nlm.nih.gov/pubmed/?term=31677924] | ISSN: | 0196-6553 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/35407 | Type: | Article | Subjects: | gentamicin/dt [Drug Therapy] *prescription treatment duration treatment indication *urinary tract infection/dt [Drug Therapy] amoxicillin plus clavulanic acid/dt [Drug Therapy] amoxicillin plus clavulanic acid/po [Oral Drug Administration] amoxicillin plus clavulanic acid/pv [Special Situation for Pharmacovigilance] *antibiotic agent/dt [Drug Therapy] *antibiotic agent/pv [Special Situation for Pharmacovigilance] cefalexin/dt [Drug Therapy] cefalexin/po [Oral Drug Administration] cefalexin/pv [Special Situation for Pharmacovigilance] cefalotin/dt [Drug Therapy] cefalotin/pv [Special Situation for Pharmacovigilance] ceftriaxone/dt [Drug Therapy] ceftriaxone/pv [Special Situation for Pharmacovigilance] ciprofloxacin/dt [Drug Therapy] ciprofloxacin/pv [Special Situation for Pharmacovigilance] clarithromycin/dt [Drug Therapy] clarithromycin/pv [Special Situation for Pharmacovigilance] clindamycin/dt [Drug Therapy] clindamycin/pv [Special Situation for Pharmacovigilance] cotrimoxazole/dt [Drug Therapy] cotrimoxazole/pv [Special Situation for Pharmacovigilance] doxycycline/dt [Drug Therapy] doxycycline/pv [Special Situation for Pharmacovigilance] gentamicin/pv [Special Situation for Pharmacovigilance] nitrofurantoin/dt [Drug Therapy] nitrofurantoin/po [Oral Drug Administration] nitrofurantoin/pv [Special Situation for Pharmacovigilance] norfloxacin/dt [Drug Therapy] norfloxacin/pv [Special Situation for Pharmacovigilance] trimethoprim/dt [Drug Therapy] trimethoprim/po [Oral Drug Administration] trimethoprim/pv [Special Situation for Pharmacovigilance] adult aged antibiotic therapy antimicrobial stewardship article Australian bedtime dosage cross-sectional study cystitis/dt [Drug Therapy] drug use female *home for the aged human major clinical study male *practice guideline gentamicin prescription treatment indication urinary tract infection amoxicillin plus clavulanic acid antibiotic agent cefalexin cefalotin ceftriaxone ciprofloxacin clarithromycin clindamycin cotrimoxazole doxycycline gentamicin nitrofurantoin norfloxacin trimethoprim aged antibiotic therapy antimicrobial stewardship Australian bedtime dosage cystitis drug use home for the aged practice guideline antimicrobial stewardship Article Australian bedtime dosage cross-sectional study cystitis / drug therapy major clinical study aged *prescription treatment duration treatment indication *urinary tract infection / *drug therapy human *home for the aged female drug use antibiotic therapy male adult *practice guideline |
Type of Clinical Study or Trial: | Observational study (cohort, case-control, cross sectional or survey) |
Appears in Collections: | Articles |
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