Please use this identifier to cite or link to this item:
https://repository.monashhealth.org/monashhealthjspui/handle/1/35867
Title: | Body size and dietary risk factors for aggressive prostate cancer: a case-control study. | Authors: | Milne R.L.;English D.R.;Hopper J.L.;Severi G.;Southey M.C.;Giles G.G.;Pal M.;Hodge A.M.;Papa N.;MacInnis R.J.;Bassett J.K.;Bolton D.;Davis I.D.;Millar J. | Institution: | (Pal) Karolinska Institute, Stockholm, Sweden (Pal, Hodge, MacInnis, Bassett, English, Southey, Milne, Giles) Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia (Hodge, MacInnis, English, Hopper, Milne, Giles) Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia (Papa, Bolton) Department of Surgery, Austin Health, The University of Melbourne, Melbourne, VIC, Australia (Bolton) Olivia Newton-John Cancer and Wellness Centre, Austin Health, Heidelberg, VIC, Australia (Davis) Monash University, Melbourne, VIC, Australia (Davis) Eastern Health, Box Hill, VIC, Australia (Millar) Alfred Health Radiation Oncology, Alfred Hospital, Melbourne, VIC, Australia (Millar) Department of Surgery, Central Clinical School, Monash University, The Alfred Centre, Melbourne, VIC, Australia (Severi) Centre de Recherche en Epidemiologie et Sante des Populations (CESP, Inserm U1018), Facultes de Medecine, Universite Paris-Saclay, UPS UVSQ, Gustave Roussy, Villejuif, France (Southey, Milne) Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia (Southey) Genetic Epidemiology Laboratory, Department of Clinical Pathology, University of Melbourne, Parkville, VIC, Australia | Issue Date: | 27-Nov-2019 | Copyright year: | 2019 | Publisher: | Springer International Publishing | Place of publication: | Switzerland | Publication information: | Cancer Causes and Control. 30 (12) (pp 1301-1312), 2019. Date of Publication: 01 Dec 2019. | Journal: | Cancer Causes and Control | Abstract: | Purpose: Diet and body size may affect the risk of aggressive prostate cancer (APC), but current evidence is inconclusive. Method(s): A case-control study was conducted in men under 75 years of age recruited from urology practices in Victoria, Australia; 1,254 with APC and 818 controls for whom the presence of prostate cancer had been excluded by biopsy. Dietary intakes were assessed using a validated food frequency questionnaire. Multivariable unconditional logistic regression estimated odds ratios and confidence intervals for hypothesized risk factors, adjusting for age, family history of prostate cancer, country of birth, socioeconomic status, smoking, and other dietary factors. Result(s): Positive associations with APC (odds ratio, 95% confidence intervals, highest vs. lowest category or quintile) were observed for body mass index (1.34, 1.02-1.78, Ptrend = 0.04), and trouser size (1.54, 1.17-2.04, Ptrend = 0.001). Intakes of milk and all dairy products were inversely associated with APC risk (0.71, 9.53-0.96, Ptrend = 0.05, and 0.64, 0.48-0.87, Ptrend = 0.012, respectively), but there was little evidence of an association with other dietary variables (Ptrend > 0.05). Conclusion(s): We confirmed previous evidence for a positive association between body size and risk of APC, and suggest that consumption of dairy products, and milk more specifically, is inversely associated with risk.Copyright © 2019, Springer Nature Switzerland AG. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1007/s10552-019-01234-7 | PubMed URL: | 31552571 [http://www.ncbi.nlm.nih.gov/pubmed/?term=31552571] | ISSN: | 0957-5243 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/35867 | Type: | Article | Subjects: | article body mass *body size *cancer risk case control study clinical assessment clinical feature clinical outcome clinical practice cohort analysis controlled study correlational study dairy product *dietary intake disease association evidence based practice family history food frequency questionnaire geographic origin major clinical study male priority journal *prostate cancer risk factor smoking socioeconomics Victoria *aggressive prostate cancer human adult age distribution aged clinical outcome clinical practice cohort analysis controlled study correlational study dairy product *dietary intake disease association evidence based practice family history food frequency questionnaire geographic origin human major clinical study male priority journal *prostate cancer clinical assessment smoking socioeconomics Victoria case control study *cancer risk *body size body mass Article risk factor clinical feature aged age distribution adult |
Type of Clinical Study or Trial: | Observational study (cohort, case-control, cross sectional or survey) |
Appears in Collections: | Articles |
Show full item record
Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.