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https://repository.monashhealth.org/monashhealthjspui/handle/1/37337| Title: | Confirmed microsporidial graft infection in a HIV-negative renal transplant recipient: A case report and review of the literature. | Authors: | Brown M.;Kanellis J.;Dendle C. ;Longano A.;Polkinghorne K.R. | Monash Health Department(s): | Infectious Diseases and Clinical Microbiology | Institution: | (Brown, Polkinghorne, Kanellis) Department of Nephrology, Monash Health, Clayton, VIC, Australia (Longano) Department of Anatomical Pathology, Monash Health, Clayton, VIC, Australia (Dendle) Monash Infectious Diseases, School of Clinical Sciences, Monash University, Prahran, VIC, Australia (Polkinghorne, Kanellis) Centre for Inflammatory Diseases, Department of Medicine, Monash University, Prahran, VIC, Australia (Polkinghorne) Department of Epidemiology and Preventive Medicine, Monash University, Prahran, VIC, Australia | Issue Date: | 18-Jun-2018 | Copyright year: | 2018 | Publisher: | Blackwell Publishing Inc. (E-mail: subscrip@blackwellpub.com) | Place of publication: | United States | Publication information: | Transplant Infectious Disease. 20 (3) (no pagination), 2018. Article Number: e12888. Date of Publication: June 2018. | Journal: | Transplant Infectious Disease | Abstract: | Microsporidia are intracellular organisms most commonly known to cause opportunistic infection in patients with human immunodeficiency virus (HIV). There have been several case reports of infection in solid organ and bone marrow transplant recipients. Here, we report a case of a non-HIV-infected renal transplant patient with microsporidiosis of the renal tract associated with acute graft dysfunction. We also review the literature of 12 previously reported cases of microsporidiosis in patients with renal transplants who had described graft involvement. We review the pattern of illness as well as the common renal biopsy features when microsporidial infection is associated with renal graft infection.Copyright © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/tid.12888 | ORCID: | Brown M.; ORCID: http://orcid.org/0000-0003-3937-1477 Dendle C.; ORCID: http://orcid.org/0000-0002-6642-5365 | Link to associated publication: | Click here for full text options | PubMed URL: | 29570921 [http://www.ncbi.nlm.nih.gov/pubmed/?term=29570921] | ISSN: | 1398-2273 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/37337 | Type: | Article | Subjects: | case report clinical article creatinine blood level disease activity drug substitution drug withdrawal end stage renal disease/su [Surgery] female *graft infection/co [Complication] *graft infection/dt [Drug Therapy] graft recipient graft versus host reaction/pc [Prevention] human human tissue kidney biopsy kidney graft rejection/dt [Drug Therapy] *kidney transplantation leukopenia lymphocytopenia *microsporidiosis/co [Complication] *microsporidiosis/dt [Drug Therapy] middle aged neutropenia plasma exchange priority journal renal graft dysfunction rheumatoid arthritis/dt [Drug Therapy] vestibular neuronitis albendazole/dt [Drug Therapy] tacrolimus/cb [Drug Combination] tacrolimus/dt [Drug Therapy] graft versus host reaction/dt [Drug Therapy] albendazole/po [Oral Drug Administration] basiliximab/cb [Drug Combination] basiliximab/dt [Drug Therapy] creatinine/ec [Endogenous Compound] hydroxychloroquine/dt [Drug Therapy] methotrexate/dt [Drug Therapy] methylprednisolone/dt [Drug Therapy] mycophenolic acid/cb [Drug Combination] mycophenolic acid/dt [Drug Therapy] pantoprazole prednisolone/cb [Drug Combination] prednisolone/dt [Drug Therapy] ranitidine salazosulfapyridine/dt [Drug Therapy] adult article bone marrow transplantation human human tissue kidney biopsy kidney graft rejection / drug therapy *kidney transplantation leukopenia lymphocytopenia *microsporidiosis / *complication / *drug therapy middle aged neutropenia plasma exchange priority journal clinical article rheumatoid arthritis / drug therapy vestibular neuronitis case report bone marrow transplantation Article adult renal graft dysfunction creatinine blood level disease activity drug substitution drug withdrawal end stage renal disease / surgery female *graft infection / *complication / *drug therapy graft recipient graft versus host reaction / drug therapy / prevention |
Type of Clinical Study or Trial: | Case series or case report |
| Appears in Collections: | Articles |
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