Please use this identifier to cite or link to this item:
https://repository.monashhealth.org/monashhealthjspui/handle/1/37605| Title: | Treatment of preeclampsia with hydroxychloroquine: a review. | Authors: | Abd Rahman R.;DeKoninck P.;Murthi P.;Wallace E.M. | Monash Health Department(s): | Obstetrics and Gynaecology (Monash Women's) | Institution: | (Abd Rahman) Department of Obstetrics and Gynecology, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia (DeKoninck, Murthi, Wallace) Department of Medicine, School of Clinical Sciences, Monash University, Monash Medical Centre, Clayton, VIC, Australia (Abd Rahman, Wallace) The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC, Australia | Issue Date: | 5-Feb-2018 | Copyright year: | 2018 | Publisher: | Taylor and Francis Ltd (E-mail: healthcare.enquiries@informa.com) | Place of publication: | United Kingdom | Publication information: | Journal of Maternal-Fetal and Neonatal Medicine. 31 (4) (pp 525-529), 2018. Date of Publication: 16 Feb 2018. | Journal: | Journal of Maternal-Fetal and Neonatal Medicine | Abstract: | In this review, we discuss the potential use of antimalarial drugs as an adjuvant therapy for preeclampsia, focusing on the mechanisms of action of this class of drugs in the context of preeclampsia. In particular, hydroxychloroquine has been shown to have various beneficial effects on patients with systemic lupus erythematosus. There are several pathways targeted by the antimalarial drugs that are similar to the pathophysiology of preeclampsia and hence offering opportunities to develop novel therapies to treat the disease. Given the safety profile of hydroxychloroquine in pregnancy, there is merit in exploring the efficacy of this drug as an adjuvant therapy in women with early onset preeclampsia.Copyright © 2017 Informa UK Limited, trading as Taylor & Francis Group. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1080/14767058.2017.1289511 | ORCID: | Murthi, Padma; ORCID: http://orcid.org/0000-0003-2535-5134 Wallace, Euan M.; ORCID: http://orcid.org/0000-0002-4506-5233 | PubMed URL: | 28142291 [http://www.ncbi.nlm.nih.gov/pubmed/?term=28142291] | ISSN: | 1476-7058 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/37605 | Type: | Review | Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
| Appears in Collections: | Articles |
Show full item record
Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.