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Title: | A review of the molecular basis for reduced endometrial receptivity in uterine fibroids and polyps. | Authors: | Tsaltas J.;Harris A.;Narula S. | Institution: | (Narula, Tsaltas) Monash University, Melbourne, VIC, Australia (Harris, Tsaltas) Department of Endoscopic Surgery, Monash Health, Melbourne, VIC, Australia (Tsaltas) Melbourne IVF, Melbourne, VIC, Australia | Issue Date: | 23-Jan-2018 | Copyright year: | 2017 | Publisher: | Wichtig Publishing Srl | Place of publication: | Italy | Publication information: | Journal of Endometriosis and Pelvic Pain Disorders. 9 (4) (pp 239-244), 2017. Date of Publication: October-December 2017. | Abstract: | The presence of fibroids and endometrial polyps is associated with reduced endometrial receptivity and subsequent fertility outcomes. The following review explores the molecular mechanisms behind reduced endometrial receptivity, with a focus upon homebox genes, basic transcription element binding proteins, transforming growth factor beta-3, and bone morphogenetic protein 2. A better understanding of these processes is essential for future targeted therapy.Copyright © 2017 Wichtig Publishing. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.5301/jeppd.5000304 | Link to associated publication: | Click here for full text options | ISSN: | 2284-0265 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/38690 | Type: | Review | Subjects: | vasculotropin/ec [Endogenous Compound] unclassified drug uvomorulin/ec [Endogenous Compound] *endometrial receptivity transcription element binding protein 1/ec [Endogenous Compound] transcription element binding protein/ec [Endogenous Compound] homeobox 10/ec [Endogenous Compound] homeobox gene clinical outcome *endometrium *endometrium polyp gene gene expression gene mutation human infertility myomectomy natural killer cell nonhuman pregnancy rate protein expression review *uterus myoma basic fibroblast growth factor receptor/ec [Endogenous Compound] bone morphogenetic protein 2/ec [Endogenous Compound] estrogen/ec [Endogenous Compound] integrin/ec [Endogenous Compound] placenta protein 14/ec [Endogenous Compound] progesterone/ec [Endogenous Compound] somatomedin binding protein 1/ec [Endogenous Compound] transforming growth factor beta3/ec [Endogenous Compound] gene gene expression gene mutation infertility myomectomy natural killer cell nonhuman pregnancy rate protein expression Review *uterus myoma human clinical outcome *endometrium *endometrium polyp |
Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
Appears in Collections: | Articles |
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