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Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/39424
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dc.contributor.authorJensen S.O.en
dc.contributor.authorvan Hal S.J.en
dc.contributor.authorEspedido B.A.en
dc.contributor.authorCoombs G.W.en
dc.contributor.authorHowden B.P.en
dc.contributor.authorKorman T.en
dc.contributor.authorNimmo G.R.en
dc.contributor.authorGosbell I.B.en
dc.date.accessioned2021-05-14T13:27:12Zen
dc.date.available2021-05-14T13:27:12Zen
dc.date.copyright2017en
dc.date.created20170519en
dc.date.issued2017-05-19en
dc.identifier.citationJournal of Antimicrobial Chemotherapy. 72 (4) (pp 998-1001), 2017. Date of Publication: 2017.en
dc.identifier.issn0305-7453en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/39424en
dc.description.abstractObjectives: To investigate the genetic context associated with the emergence of vanA VRE in Australia. Method(s): The whole genomes of 18 randomly selected vanA-positive Enterococcus faecium patient isolates, collected between 2011 and 2013 from hospitals in four Australian capitals, were sequenced and analysed. Result(s): In silico typing and transposon/plasmid assembly revealed that the sequenced isolates represented (in most cases) different hospital-adapted STs and were associated with a variety of different Tn1546 variants and plasmid backbone structures. Conclusion(s): The recent emergence of vanA VRE in Australia was polyclonal and not associatedwith the dissemination of a single 'dominant' ST or vanA-encoding plasmid. Interestingly, the factors contributing to this epidemiological change are not known and future studies may need to consider investigation of potential community sources.Copyright © The Author 2016.en
dc.languageEnglishen
dc.languageenen
dc.publisherOxford University Press (E-mail: jnl.info@oup.co.uk)en
dc.relation.ispartofJournal of Antimicrobial Chemotherapyen
dc.titlePolyclonal emergence of vanA vancomycin-resistant Enterococcus faecium in Australia.en
dc.typeArticleen
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1093/jac/dkw539en
dc.publisher.placeUnited Kingdomen
dc.identifier.pubmedid28031272 [http://www.ncbi.nlm.nih.gov/pubmed/?term=28031272]en
dc.identifier.source615846573en
dc.identifier.institution(van Hal, Espedido, Gosbell, Jensen) School of Medicine, Western Sydney University, Sydney, NSW, Australia (van Hal) Royal Prince Alfred Hospital, Sydney, NSW, Australia (Espedido, Gosbell, Jensen) Antimicrobial Resistance and Mobile Elements Group, Ingham Institute for Applied Medical Research, Sydney, NSW, Australia (Coombs) School of Veterinary and Life Sciences, Murdoch University, Perth, WA, Australia (Coombs) PathWest Laboratory Medicine, Fiona Stanley Hospital, Perth, WA, Australia (Howden) Austin Health, Melbourne, VIC, Australia (Howden) Department of Microbiology and Immunology, The University of Melbourne, Melbourne, VIC, Australia (Korman) Monash Hospital, Melbourne, VIC, Australia (Nimmo) Pathology Queensland, Brisbane, QLD, Australia (Gosbell) Sydney South Western Pathology Service, NSW Pathology, Sydney, NSW, Australiaen
dc.description.addressS.O. Jensen, School of Medicine, Western Sydney University, Penrith, NSW 2751, Australia. E-mail: s.jensen@westernsydney.edu.auen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2017 Elsevier B.V., All rights reserved.en
dc.identifier.authoremailJensen S.O.; s.jensen@westernsydney.edu.auen
dc.description.grantNo: GTN1105905 Organization: (NHMRC) *National Health and Medical Research Council*en
dc.identifier.affiliationext(van Hal, Espedido, Gosbell, Jensen) School of Medicine, Western Sydney University, Sydney, NSW, Australia-
dc.identifier.affiliationext(van Hal) Royal Prince Alfred Hospital, Sydney, NSW, Australia-
dc.identifier.affiliationext(Espedido, Gosbell, Jensen) Antimicrobial Resistance and Mobile Elements Group, Ingham Institute for Applied Medical Research, Sydney, NSW, Australia-
dc.identifier.affiliationext(Coombs) School of Veterinary and Life Sciences, Murdoch University, Perth, WA, Australia-
dc.identifier.affiliationext(Coombs) PathWest Laboratory Medicine, Fiona Stanley Hospital, Perth, WA, Australia-
dc.identifier.affiliationext(Howden) Austin Health, Melbourne, VIC, Australia-
dc.identifier.affiliationext(Howden) Department of Microbiology and Immunology, The University of Melbourne, Melbourne, VIC, Australia-
dc.identifier.affiliationext(Nimmo) Pathology Queensland, Brisbane, QLD, Australia-
dc.identifier.affiliationext(Gosbell) Sydney South Western Pathology Service, NSW Pathology, Sydney, NSW, Australia-
dc.identifier.affiliationmh(Korman) Monash Hospital, Melbourne, VIC, Australia-
dc.contributor.affiliationInfectious Diseases and Clinical Microbiology-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeArticle-
crisitem.author.deptInfectious Diseases and Clinical Microbiology-
crisitem.author.deptPathology-
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