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Title: | Glioblastoma with primitive neuronal pattern in a girl aged 3 months: A rare diagnosis at an unusual age. | Authors: | Tan C.H.;Phung T.B.;Xenos C. | Monash Health Department(s): | Pathology Neurosurgery |
Institution: | (Tan, Xenos) Department of Neurosurgery, Monash Health, Clayton, VIC, Australia (Phung) Department of Anatomical Pathology, Monash Health, Clayton, VIC, Australia | Issue Date: | 9-Mar-2017 | Copyright year: | 2017 | Publisher: | BMJ Publishing Group (E-mail: subscriptions@bmjgroup.com) | Place of publication: | United Kingdom | Publication information: | BMJ Case Reports. 2017 (no pagination), 2017. Article Number: 218617. Date of Publication: 2017. | Journal: | BMJ Case Reports | Abstract: | A girl aged 3 months presented with multiple seizures within 12 hours and was noted to have a palpable swelling over the right temporal region. MRI of the brain revealed a large right frontotemporal tumour, suggestive of supratentorial primitive neuroectodermal tumour. She underwent a stealth-guided craniotomy and debulking of the tumour. Histopathology and immunochemistry of the specimen, however, indicated a high-grade tumour with glioblastoma and neuroblastic components. She underwent adjuvant chemotherapy following the surgery and is well at 7-month follow-up. This case underscores the importance of considering the rare entity of glioblastoma with primitive neuronal pattern as a differential diagnosis in a young child.Copyright © 2017 BMJ Publishing Group. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1136/bcr-2016-218617 | PubMed URL: | 28202484 [http://www.ncbi.nlm.nih.gov/pubmed/?term=28202484] | ISSN: | 1757-790X (electronic) | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/39524 | Type: | Article | Type of Clinical Study or Trial: | Case series or case report |
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