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Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/39587
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dc.contributor.authorWilliams T.en
dc.contributor.authorMcLean C.A.en
dc.contributor.authorButler E.en
dc.contributor.authorFok A.en
dc.date.accessioned2021-05-14T13:30:43Zen
dc.date.available2021-05-14T13:30:43Zen
dc.date.copyright2016en
dc.date.created20171227en
dc.date.issued2017-12-27en
dc.identifier.citationMultiple Sclerosis Journal. 22 (11) (pp 1495-1498), 2016. Date of Publication: 01 Oct 2016.en
dc.identifier.issn1352-4585en
dc.identifier.urihttps://repository.monashhealth.org/monashhealthjspui/handle/1/39587en
dc.description.abstractWe report two patients with relapsing remitting multiple sclerosis (RRMS) on interferon (IFN) beta-1a treatment for more than 7 years who developed pulmonary arterial hypertension (PAH). Patient 1 developed severe PAH requiring lung transplantation. Histology showed typical proliferative lesions including plexiform lesions consistent with PAH. Patient 2 ceased IFN beta-1a, and their symptoms stabilised. Both cases highlight IFN beta-1a treatment as a potential risk factor for PAH. PAH needs to be considered as a diagnosis in patients on long-term IFN beta-1a treatment who develop new-onset respiratory symptoms.Copyright © The Author(s), 2015.en
dc.languageEnglishen
dc.languageenen
dc.publisherSAGE Publications Ltd (E-mail: info@sagepub.co.uk)en
dc.relation.ispartofMultiple Sclerosis Journalen
dc.titleInterferon beta-1a long-term therapy related to pulmonary arterial hypertension in multiple sclerosis patients.en
dc.typeArticleen
dc.type.studyortrialCase series or case report-
dc.identifier.doihttp://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1177/1352458515618020en
dc.publisher.placeUnited Kingdomen
dc.identifier.source619851971en
dc.identifier.institution(Fok) Department of Ophthalmology & Visual Sciences, Faculty of Medicine, Eye Care Centre (Vancouver General Hospital), Vancouver, BC, Canada (Fok, Butler) Department of Neurosciences, Monash Health, Melbourne, VIC, Australia (Williams) Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Monash University, Melbourne, VIC, Australia (McLean) Department of Anatomical Pathology, Alfred Hospital, Melbourne, VIC, Australiaen
dc.description.addressA. Fok, Department of Ophthalmology & Visual Sciences, Faculty of Medicine, Eye Care Centre (Vancouver General Hospital), 2550 Willow Street, Vancouver, BC V5Z 3N9, Canada. E-mail: anfernee45@hotmail.comen
dc.description.publicationstatusEmbaseen
dc.rights.statementCopyright 2017 Elsevier B.V., All rights reserved.en
dc.subect.keywordsBeta-interferon Interferon Multiple sclerosis Pulmonary arterial hypertensionen
dc.identifier.authoremailFok A.; anfernee45@hotmail.comen
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeArticle-
crisitem.author.deptNeurology-
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