Please use this identifier to cite or link to this item:
https://repository.monashhealth.org/monashhealthjspui/handle/1/39904| Title: | Targeting plasma cells: Are we any closer to a panacea for diseases of antibody-secreting cells?. | Authors: | Low M. ;Tarlinton D.;Grigoriadis G. ;Infantino S. | Institution: | (Low, Infantino, Tarlinton) Immunology Division, Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville, VIC, Australia (Low, Grigoriadis, Tarlinton) Department of Haematology, Monash Health, Monash Hospital, Clayton, VIC, Australia (Low, Infantino) Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia (Grigoriadis) School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia (Grigoriadis) Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia (Grigoriadis) Malignant Haematology and Stem Cell Transplantation Service and Alfred Pathology Service, The Alfred, Melbourne, VIC, Australia | Issue Date: | 25-Feb-2016 | Copyright year: | 2016 | Publisher: | Blackwell Publishing Ltd (E-mail: customerservices@oxonblackwellpublishing.com) | Place of publication: | United Kingdom | Publication information: | Immunological Reviews. 270 (1) (pp 78-94), 2016. Date of Publication: 01 Mar 2016. | Journal: | Immunological Reviews | Abstract: | Antibody-secreting cells (ASCs) are critical for a functional and effective adaptive immune system. In a number of illnesses, however, these same cells contribute to the underlying disease state leading to significant morbidity and mortality. While therapeutic targeting of antibody-secreting cells has progressed significantly over the last two decades, many of these conditions remain major health problems. In this review, we will discuss current and potential therapeutic targeting of ASCs in the context of the known biology of these cells.Copyright © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/imr.12388 | PubMed URL: | 26864106 [http://www.ncbi.nlm.nih.gov/pubmed/?term=26864106] | ISSN: | 0105-2896 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/39904 | Type: | Review | Type of Clinical Study or Trial: | Review article (e.g. literature review, narrative review) |
| Appears in Collections: | Articles |
Show full item record
Items in Monash Health Research Repository are protected by copyright, with all rights reserved, unless otherwise indicated.