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Title: | Trends in incidence and survival for upper tract urothelial cancer (UTUC) in the state of Victoria - Australia. | Authors: | Aw H.C.;Persad R.;Woodford R.;Ranasinghe W.;Sengupta S. | Institution: | (Woodford, Ranasinghe, Aw) Department of Urology, Monash Medical Centre, 823-865 Centre Road Bentleigh, Melbourne, VIC 3165, Australia (Ranasinghe) Launceston General Hospital, TAS, Australia (Sengupta) Austin Health, Melbourne, VIC, Australia (Persad) Bristol Urological Institute, Bristol, United Kingdom | Issue Date: | 4-May-2016 | Copyright year: | 2016 | Publisher: | Blackwell Publishing Ltd (E-mail: customerservices@oxonblackwellpublishing.com) | Place of publication: | United Kingdom | Publication information: | BJU International. 117 (Supplement 4) (pp 45-49), 2016. Date of Publication: 01 Apr 2016. | Journal: | BJU International | Abstract: | Objective To investigate the incidence and mortality trends of upper tract urothelial cancers (UTUC) in Victoria over the last decade. Patients and Methods Age-adjusted incidence and mortality rates were calculated for UTUC. These were identified using data from the Victorian Cancer Registry from 2001 until 2011 based on histological diagnoses. Age at diagnosis, sex and demographical location were compared. Results The age-standardised incidence of UTUC remained stable from 2001 to 2011. There were 278 deaths from UTUC over this period with an overall 5-year survival rate of 32%. There was no significant difference in survival between 2001-06 and 2007-11 (30% vs 36%, respectively). Lower age at diagnosis was associated with a significant improvement in survival (P = 0.01). Sex and geographical location appeared to have no effect on survival. Conclusion The 5-year survival rates for UTUC in Victoria are poor, particularly in comparison to worldwide data. In contrast to worldwide trends, the incidence of UTUC appears to be stable. No significant improvement in 5-year survival rates over the short study period was identified. These findings highlight the difficulties in managing this rare yet deadly malignancy.Copyright © 2016 The Authors. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/bju.13232 | PubMed URL: | 26486693 [http://www.ncbi.nlm.nih.gov/pubmed/?term=26486693] | ISSN: | 1464-4096 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/39919 | Type: | Article | Subjects: | male overall survival preschool child priority journal school child survival rate survival time trend study *urinary tract cancer/di [Diagnosis] *urinary tract cancer/ep [Epidemiology] very elderly young adult *upper tract urothelial cancer/di [Diagnosis] *upper tract urothelial cancer/ep [Epidemiology] middle aged adult age aged article Australia cancer diagnosis *cancer incidence cancer mortality cancer registry *cancer survival child female geographic distribution histopathology human human tissue major clinical study child female geographic distribution histopathology human human tissue major clinical study male middle aged overall survival preschool child priority journal school child survival rate survival time trend study *urinary tract cancer / *diagnosis / *epidemiology age young adult adult very elderly aged Article Australia cancer diagnosis *cancer incidence cancer mortality cancer registry *cancer survival |
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