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https://repository.monashhealth.org/monashhealthjspui/handle/1/40796| Title: | Managing psychosis in a renal transplant recipient with bipolar affective disorder and allograft rejection. | Authors: | Kanellis J.;Mulley W. ;Summers S.;Dave V. | Institution: | (Dave, Mulley, Kanellis, Summers) Department of Nephrology, Monash Health, 246 Clayton Road, Clayton, VIC 3168, Australia (Mulley, Kanellis, Summers) Department of Medicine, Monash University, Melbourne, VIC, Australia | Issue Date: | 8-Apr-2015 | Copyright year: | 2015 | Publisher: | Blackwell Publishing (E-mail: info@asia.blackpublishing.com.au) | Place of publication: | Australia | Publication information: | Nephrology. 20 (S1) (pp 2-5), 2015. Date of Publication: 01 Mar 2015. | Journal: | Nephrology | Abstract: | Management of mental health issues in the post-transplant setting can be difficult given the potential for medication related neurotoxicity. The lack of established guidelines in this area further compounds this difficulty. The current report details the course of patient with stable bipolar affective disorder prior to renal transplantation, who developed de novo psychosis post-transplantation as an adverse effect of her tacrolimus therapy. The patient was unable to take her usual oral immunosuppressants due to the severity of her psychosis and she eventually required alemtuzumab parenterally as rescue therapy from rejection. This case highlights the diagnostic and therapeutic challenges when dealing with transplant recipients with significant psychosis.Copyright © 2015 Asian Pacific Society of Nephrology. | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/nep.12419 | PubMed URL: | 25807849 [http://www.ncbi.nlm.nih.gov/pubmed/?term=25807849] | ISSN: | 1320-5358 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/40796 | Type: | Review | Subjects: | bipolar disorder/dt [Drug Therapy] case report creatinine blood level drug dose increase drug withdrawal end stage renal disease/co [Complication] end stage renal disease/th [Therapy] evening dosage female graft failure/co [Complication] *graft recipient *graft rejection/co [Complication] *graft rejection/dt [Drug Therapy] graft rejection/dt [Drug Therapy] grandiose delusion human immunosuppressive treatment kidney biopsy *kidney graft kidney transplantation low drug dose maintenance therapy mental health middle aged morning dosage nephrotoxicity plasmapheresis postoperative complication/co [Complication] practice guideline priority journal *psychosis/si [Side Effect] psychosis/si [Side Effect] review alemtuzumab/dt [Drug Therapy] basiliximab/dt [Drug Therapy] haloperidol/cb [Drug Combination] haloperidol/dt [Drug Therapy] HLA antigen immunoglobulin/iv [Intravenous Drug Administration] immunosuppressive agent methylprednisolone/dt [Drug Therapy] methylprednisolone/iv [Intravenous Drug Administration] mycophenolic acid 2 morpholinoethyl ester/dt [Drug Therapy] prednisolone/dt [Drug Therapy] prednisolone/pa [Parenteral Drug Administration] rapamycin tacrolimus/ae [Adverse Drug Reaction] kidney function benzatropine/cb [Drug Combination] benzatropine/dt [Drug Therapy] carbamazepine/cb [Drug Combination] carbamazepine/dt [Drug Therapy] clonazepam/cb [Drug Combination] clonazepam/dt [Drug Therapy] creatinine/ec [Endogenous Compound] cyclosporin/dt [Drug Therapy] cytochrome P450 everolimus/dt [Drug Therapy] everolimus/pa [Parenteral Drug Administration] acute psychosis adult antibody mediated rejection auditory hallucination *bipolar disorder/dt [Drug Therapy] end stage renal disease / complication / therapy evening dosage female graft failure / complication *graft recipient *graft rejection / *complication / *drug therapy graft rejection / drug therapy grandiose delusion human immunosuppressive treatment kidney biopsy kidney function *kidney graft kidney transplantation low drug dose maintenance therapy mental health middle aged morning dosage nephrotoxicity plasmapheresis postoperative complication / complication adult priority journal *psychosis / *side effect psychosis / side effect Review acute psychosis practice guideline antibody mediated rejection auditory hallucination *bipolar disorder / *drug therapy bipolar disorder / drug therapy case report creatinine blood level drug dose increase drug withdrawal |
Type of Clinical Study or Trial: | Case series or case report |
| Appears in Collections: | Articles |
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