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https://repository.monashhealth.org/monashhealthjspui/handle/1/45666| Conference/Presentation Title: | Mental health during pregnancy and post-partum in mothers with and without type 1 diabetes: The ENDIA study. | Authors: | Hall M.;Oakey H.;Penno M.;McGorm K.;Anderson A. ;Ashwood P.;Colman P.;Craig M.;Davis E.;Harris M. ;Harrison L.;Haynes A.;Sinnott R.;Soldatos G. ;Vuillermin P.;Wentworth J.;Thomson R.;Couper J. | Monash Health Department(s): | Diabetes and Vascular Medicine | Institution: | (Soldatos) Monash Health, Diabetes and Vascular Medicine Unit, Melbourne, Australia (Hall, Oakey, Penno, McGorm, Anderson, Ashwood, Thomson, Couper) Robinson Research Institute, University of Adelaide, Adelaide, Australia (Hall, Couper) Women's and Children's Hospital, Department of Diabetes and Endocrinology, Adelaide, Australia (Colman, Wentworth) Royal Melbourne Hospital, Department of Diabetes and Endocrinology, Melbourne, Australia (Craig) University of New South Wales, School of Women's and Children's Health, Faculty of Medicine, Sydney, Australia (Craig) Institute of Endocrinology and Diabetes, Children's Hospital at Westmead, Sydney, Australia (Davis, Haynes) Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Australia (Harris) University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Australia (Harris) Queensland Children's Hospital, South Brisbane, Australia (Harrison, Wentworth) Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia (Sinnott) Melbourne eResearch Group, School of Computing and Information Services, University of Melbourne, Melbourne, Australia (Soldatos) Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia (Vuillermin) Deakin University, Faculty of Health, School of Medicine, Geelong, Australia (Vuillermin) Child Health Research Unit, Barwon Health, Geelong, Australia |
Presentation/Conference Date: | 6-Dec-2021 | Copyright year: | 2021 | Publisher: | Blackwell Publishing Ltd | Publication information: | Pediatric Diabetes. Conference: 47th Annual Conference of the International Society for Pediatric and Adolescent Diabetes, ISPAD 2021. Virtual. 22(SUPPL 30) (pp 153-154), 2021. Date of Publication: October 2021. | Journal: | Pediatric Diabetes | Abstract: | Introduction: We aimed to compare the mental health of mothers, with and without type 1 diabetes (T1D), during pregnancy and postpartum, and to examine the relationship between glycaemic control and mental health in T1D. Objective(s): We hypothesised that mental health in trimester 3 (T3) and post-partum is less favourable in mothers with T1D, and that poorer mental health scores relate directly to glycaemic control. Method(s): Participants were 800/946 women enrolled in the Environmental Determinants of Islet Autoimmunity (ENDIA) study, an Australiawide pregnancy-birth prospective cohort following children with a first-degree relative with T1D, from 2016-2020.Women with and without T1D (n=518, 282) completed the Edinburgh Postnatal Depression Scale (EPDS) and Perceived Stress Scale (PSS) during T3, (median [IQR], 34 [32, 36] weeks) and early post-partum (median 14 [13, 16] weeks). Linear mixed regression models were adjusted for parity. Result(s): Women without T1D were aged mean (SD) 33.1 (4.4) years; 31.9 (4.4) years with T1D. Pre-existing mental health issues requiring psychotropic medications were of similar number in non-T1D n=17 [6%] and T1D n=41 [8%]. EPDS and PSS scores did not differ between non-T1D and T1D mothers at T3 or post-partum (all p>=0.5; Table 1). EPDS scores were less favourable at T3 compared with postpartum (p=0.01), independent of T1D status, and by post-partum 12/47 women had improved to below the threshold (=12) recommended for intervention. HbA1c during pregnancy in 398/518 women (76.8%) with T1D did not relate to EPDS (r2=0.01, p=0.2) or PSS (r2=0.02, p=0.4) scores. Median [IQR] HbA1c was 6.3% [5.8-6.9]. Conclusion(s): Overall, mental health in late pregnancy and postpartum was not adversely impacted by T1D. Glycaemic control did not relate to mental health scores in mothers with T1D. A generalised improvement in mental health between T3 and post-partum was independent of T1D status. | Conference Name: | 47th Annual Conference of the International Society for Pediatric and Adolescent Diabetes, ISPAD 2021 | Conference Start Date: | 20211-0-13 | Conference End Date: | 20211-0-15 | Conference Location: | Virtual | DOI: | http://monash.idm.oclc.org/login?url=http://dx.doi.org/10.1111/pedi.13269 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/45666 | Type: | Conference Abstract | Subjects: | autoimmunity Edinburgh Postnatal Depression Scale glycemic control insulin dependent diabetes mellitus mental health mother pancreas islet parity Perceived Stress Scale third trimester pregnancy hemoglobin A1c psychotropic agent |
Type of Clinical Study or Trial: | Observational study (cohort, case-control, cross sectional or survey) |
| Appears in Collections: | Conference Abstracts |
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