Please use this identifier to cite or link to this item: https://repository.monashhealth.org/monashhealthjspui/handle/1/51832
Title: The clinical and radiological outcomes of the multimodal use of the woven endobridge (WEB) device: a large multicentre study.
Authors: Nasra M.;Pavlin-Premrl D.;Protto S.;Khabaza A.;Gan C.;Siasat P.;Jhamb A.;Smith P.;Moore J.;Russell J.;Ren Y.;Slater L.-A.;Chandra R.V.;Chong W.;Shaygi B.;Brooks M.;Maingard J.;Asadi H.
Monash Health Department(s): Radiology
Neurosurgery
Institution: (Nasra) Department of Medicine, Northern Health, Epping, Melbourne, VIC
(Pavlin-Premrl) Department of Neurology, Austin Health, Heidelberg, Melbourne VIC; Department of Interventional Neuroradiology, Austin Health, Melbourne VIC; Department of Interventional Neuroradiology, St Vincent's Health, Fitzroy VIC
(Protto, Gan, Slater, Chandra, Chong) Department of Interventional Neuroradiology, Monash Health, Clayton, VIC
(Khabaza) Department of Interventional Neuroradiology, Austin Health, Melbourne VIC; Department of Interventional Neuroradiology, St Vincent's Health, Fitzroy VIC; Department of Interventional Neuroradiology, Monash Health, Clayton, VIC
(Siasat) Department of Surgery, St. Vincent's Health, VIC, Slovenia
(Jhamb) Department of Radiology, St Vincent's Health, VIC, Slovenia
(Smith) Department of Neurosurgery, St. Vincent's Health, Fitzroy, Melbourne; Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Melbourne
(Moore) Department of Neurosurgery, Clayton VIC, Monash Health
(Russell) Department of Neurosurgery, Austin Health, Heidelberg, VIC
(Ren) Department of Radiology, Austin Health, Heidelberg, VIC
(Shaygi) Department of Interventional Radiology, London North West University Healthcare NHS Trust, London, United Kingdom
(Brooks) Department of Interventional Neuroradiology, Austin Health, Melbourne VIC; Department of Interventional Neuroradiology, St Vincent's Health, Fitzroy VIC
(Maingard) Department of Interventional Neuroradiology, Austin Health, Melbourne VIC; Department of Interventional Neuroradiology, St Vincent's Health, Fitzroy VIC; School of Medicine, Deakin University, Waurn Ponds, Victoria, Australia
(Asadi) Department of Interventional Neuroradiology, Austin Health, Melbourne VIC; Department of Interventional Neuroradiology, Monash Health, Clayton, VIC; School of Medicine, Deakin University, Waurn Ponds, Victoria, Australia
Issue Date: 24-May-2024
Copyright year: 2024
Place of publication: United States
Publication information: World Neurosurgery. (no pagination), 2024. Date of Publication: 17 May 2024.
Journal: World Neurosurgery
Abstract: BACKGROUND: The Woven EndoBridge (WEB) is a device used for intrasaccular flow diversion, designed for the elimination of wide-necked bifurcation aneurysms (WNBAs) from the circulation. In this study, we aim to assess the safety and efficacy of the WEB, and its uses in treating aneurysms of different morphologies and locations. METHOD(S): In a retrospective analysis, we compiled a comprehensive dataset from patients treated with the WEB device across three major Australian neurovascular centres from May 2017 to September 2023. The case series encompassed a spectrum of aneurysm types, including wide-necked bifurcation, sidewall, and irregularly shaped aneurysms, as well as cases previously managed with alternative therapeutic strategies. This study additionally encompasses cases where aneurysms were managed using the WEB device in combination with supplementary endovascular devices. RESULT(S): The study included 169 aneurysms in 161 patients. The rate of satisfactory aneurysm occlusion was 85.6%, with 86.7% of patients maintaining good functional status at their most recent follow-up. The procedure exhibited a low mortality rate of 0.6% and a thromboembolic complication rate of 7.1% (n=12/161). There were no instances of post-operative re-rupture and the procedure-related haemorrhage rate was low (1.2%, n=2/169), aligning with the literature regarding the safety and efficacy of the WEB device. CONCLUSION(S): Our multicentre trial reinforces the WEB device's role as an effective and safe modality for intracranial aneurysm management, supporting its expanded application beyond WNBAs. Further prospective studies are required to delineate its evolving role fully.Copyright © 2024. Published by Elsevier Inc.
DOI: http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1016/j.wneu.2024.05.076
PubMed URL: 38763461 [https://www.ncbi.nlm.nih.gov/pubmed/?term=38763461]
URI: https://repository.monashhealth.org/monashhealthjspui/handle/1/51832
Type: Article
Subjects: intracranial aneurysm
subarachnoid hemorrhage
thromboembolism
vascular plug
Type of Clinical Study or Trial: Observational study (cohort, case-control, cross sectional, or survey)
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