Victorian Lung Cancer Registry Impacts on Multi- Disciplinary Lung Cancer Meeting Presentation.

Abstract

Introduction: Lung cancer is an heterogeneous and complex disease requiring multidisciplinary input for optimal management planning, with guidelines recommending all patients be discussed in a multidisciplinary setting. Multidisciplinary discussion (MDM) aims to enhance evidencebased management, improve treatment access and optimise complex management plans. Method(s): We aimed to assess the extent and impacts of M D M discussion in patients with lung cancer described by the Victorian Lung Cancer Registry (VLCR) from 2011-2024 in Victoria, Australia. We identified MDM presented and non-presented patients and assessed dependant management outcomes and survival impacts. Result(s): 18,597 patients were included of w h om 6 7% had evidence of presentation to a lung cancer MDM, with MDM presentation increasing from 59.1% to 80.6% during the study period Figure 1. M D M presentation was associ ated with significantly higher levels of provision of Guideline Concordant Treatment (GCT) i n NSCLC (52.9% vs 42.3%, p<0.001), non-GCT and lower levels of no treatment (13.4% vs 24.6%, p<0.001). Modifiable factors which may increase MDM presentation included higher age, stage IV disease and treatment in a private hospital. Propensity matched sur vival analysis in NSCLC revealed a median survival of 1.1 years (1.0-1.3 years, p<0.001) for M D M presented vs non presented individuals 0.86 years (0.76-0.94), providing a 1 2% reduction in mortality hazard (HR 0.88(0.82-0.95), p<0.001) Figure 2. Conclusion(s): Clinical Quality Regis tries enable assessment of the appropriateness and effectiveness of healthcare implementation in population-based complex disease domains and inform quality improvement initiatives within learning health sys tems. MDM presentation increased by 20% during this study period providing significant management optimisation and survival advantage.