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https://repository.monashhealth.org/monashhealthjspui/handle/1/58199| Title: | Ultra-processed food intake, cognitive function, and dementia risk: A cross-sectional study of middle-aged and older Australian adults. | Authors: | Cardoso B.R.;Steele E.M.;Brayner B.;Yuan X.;Bransby L.;Cummins H.;Lim Y.Y.;Machado P. | Monash Health Department(s): | Monash University - School of Clinical Sciences at Monash Health | Institution: | (Cardoso, Yuan) Department of Nutrition, Dietetics and Food, Monash University, Clayton, VIC, Australia (Cardoso) Victorian Heart Institute, Monash University, Clayton, VIC, Australia (Steele) Department of Nutrition, School of Public Health, University of Sao Paulo, SP, Sao Paulo, Brazil (Steele) Center for Epidemiological Studies in Health and Nutrition, University of Sao Paulo, SP, Sao Paulo, Brazil (Brayner, Machado) Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia (Bransby, Cummins, Lim) Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, VIC, Australia |
Issue Date: | 26-Apr-2026 | Copyright year: | 2026 | Publisher: | John Wiley and Sons Inc | Place of publication: | United States | Publication information: | Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 18(2) (no pagination), 2026. Article Number: e70335. Date of Publication: 01 Apr 2026. | Journal: | Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring | Abstract: | INTRODUCTION: Ultra-processed food (UPF) consumption is linked to over 30 adverse health outcomes, including several risk factors for dementia such as cardiovascular disease, type 2 diabetes, and obesity. We aimed to examine the association of UPF consumption with cognitive performance and dementia risk scores, and whether these associations are independent of overall diet quality. METHOD(S): This cross-sectional analysis assessed 2,192 Australian dementia-free adults aged 40-70 years. Diet was assessed using a validated food frequency questionnaire and classified according to the Nova system. Cognitive function was measured using the Cogstate Brief Battery, and dementia risk was estimated with the CAIDE tool. RESULT(S): Each 10% increase in UPF intake was associated with lower attention scores (-0.05 points) and higher dementia risk (+0.24 points), independent of Mediterranean diet adherence. DISCUSSION(S): Higher UPF consumption is associated with poorer attention and increased modifiable dementia risk, independent of overall diet quality.Copyright © 2026 The Author(s). Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals LLC on behalf of Alzheimer's Association. | DOI: | http://monash.idm.oclc.org/login?url=https://dx.doi.org/10.1002/dad2.70335 | URI: | https://repository.monashhealth.org/monashhealthjspui/handle/1/58199 | Type: | Article | Subjects: | Australian aged Alzheimer disease cardiovascular disease cognition dementia diet diet quality dietary compliance etiology food frequency food intake healthy diet Mediterranean diet mental performance non insulin dependent diabetes mellitus obesity ultra-processed food |
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